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Table 2 Multivariate logistic regression analysis comparing wards patients against critically ill patients (Enter method)

From: Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

  OR [CI95%] p OR [CI95%] p OR [CI95%] p
Sex (male) 2.055 [0.656–6.432 0.216 1.647 [0.508–5.337] 0.406 1.608 [0.500–5.166] 0.425
Systolic pressure (mmHg) 0.985 [0.960–1.011 0.253 0.984 [0.958–1.011] 0.247 0.984 [0.957–1.012] 0.261
O2 Saturation (%) 1.069 [0.986–1.160] 0.107 1.076 [0.992–1.167] 0.079 1.082 [0.993–1.180] 0.071
Bilateral pulmonary infiltrate 2.343 [0.469–11.707] 0.300 3.088 [0.566–16.852] 0.193 3.064 [0.539–17.430] 0.207
Glucose (mg/dl) 1.008 [1.001–1.015] 0.028 1.007 [1.000–1.015] 0.061 1.007 [0.999–1.014] 0.070
INR 1.123 [0.433–2.915] 0.812 1.245 [0.469–3.305] 0.661 1.377 [0.519–3.657] 0.521
D-dimer (pg/mL) 1.000 [1.000–1.000] 0.294 1.000 [1.000–1.000] 0.190 1.000 [1.000–1.000] 0.420
LDH (UI/L) 1.009 [1.004–1.014] 0.000 1.008 [1.003–1.013] 0.002 1.009 [1.004–1.014] 0.001
GPT (UI/L) 1.005 [0.992–1.019] 0.443 1.005 [0.991–1.019] 0.516 1.006 [0.992–1.021] 0.402
Ferritin (pg/mL) 1.000 [1.000–1.000] 0.705 1.000 [1.000–1.000] 0.856 1.000 [1.000–1.000] 0.835
CRP (mg/dl) 0.998 [0.992–1.003] 0.420 0.999 [0.993–1.005] 0.749 0.998 [0.993–1.004] 0.547
Haematocrit (%) 0.770 [0.676–0.877] 0.000 0.762 [0.665–0.872] 0.000 0.737 [0.633–0.858] 0.000
SARS-CoV-2 IgG (Yes) 1.967 [0.627 -6.170] 0.246 1.835 [0.562–5.987] 0.315 1.918 [0.577–6.377] 0.288
Lymphocytes (cells/mm3) 0.998 [0.996–1.000] 0.011 0.998 [0.996–1.000] 0.012 0.998 [0.996–0.999] 0.010
Monocytes (cells/mm3) 0.998 [0.995–1.001] 0.180 0.998 [0.995–1.001] 0.212 0.999 [0.996–1.002] 0.463
Neutrophils (cells/mm3) 1.000 [1.000–1.000] 0.262 1.000 [1.000–1.000] 0.326 1.000 [1.000–1.000] 0.239
Viral RNAemia (Yes) 3.916 [1.183–12.968] 0.025
Viral RNA load (N1)
in plasma, log (copies/mL)
1.962 [1.244–3.096] 0.004
Viral RNA load (N2)
in plasma, log (copies/mL)
2.229 [1.382–3.595] 0.001
  1. The association between viral RNAemia or viral RNA load targeting the N1 region, or viral RNA load targeting the N2 region with critical illness was evaluated adjusting by major confounding factors