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Table 2 Multivariate logistic regression analysis comparing wards patients against critically ill patients (Enter method)

From: Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

 

OR [CI95%]

p

OR [CI95%]

p

OR [CI95%]

p

Sex (male)

2.055 [0.656–6.432

0.216

1.647 [0.508–5.337]

0.406

1.608 [0.500–5.166]

0.425

Systolic pressure (mmHg)

0.985 [0.960–1.011

0.253

0.984 [0.958–1.011]

0.247

0.984 [0.957–1.012]

0.261

O2 Saturation (%)

1.069 [0.986–1.160]

0.107

1.076 [0.992–1.167]

0.079

1.082 [0.993–1.180]

0.071

Bilateral pulmonary infiltrate

2.343 [0.469–11.707]

0.300

3.088 [0.566–16.852]

0.193

3.064 [0.539–17.430]

0.207

Glucose (mg/dl)

1.008 [1.001–1.015]

0.028

1.007 [1.000–1.015]

0.061

1.007 [0.999–1.014]

0.070

INR

1.123 [0.433–2.915]

0.812

1.245 [0.469–3.305]

0.661

1.377 [0.519–3.657]

0.521

D-dimer (pg/mL)

1.000 [1.000–1.000]

0.294

1.000 [1.000–1.000]

0.190

1.000 [1.000–1.000]

0.420

LDH (UI/L)

1.009 [1.004–1.014]

0.000

1.008 [1.003–1.013]

0.002

1.009 [1.004–1.014]

0.001

GPT (UI/L)

1.005 [0.992–1.019]

0.443

1.005 [0.991–1.019]

0.516

1.006 [0.992–1.021]

0.402

Ferritin (pg/mL)

1.000 [1.000–1.000]

0.705

1.000 [1.000–1.000]

0.856

1.000 [1.000–1.000]

0.835

CRP (mg/dl)

0.998 [0.992–1.003]

0.420

0.999 [0.993–1.005]

0.749

0.998 [0.993–1.004]

0.547

Haematocrit (%)

0.770 [0.676–0.877]

0.000

0.762 [0.665–0.872]

0.000

0.737 [0.633–0.858]

0.000

SARS-CoV-2 IgG (Yes)

1.967 [0.627 -6.170]

0.246

1.835 [0.562–5.987]

0.315

1.918 [0.577–6.377]

0.288

Lymphocytes (cells/mm3)

0.998 [0.996–1.000]

0.011

0.998 [0.996–1.000]

0.012

0.998 [0.996–0.999]

0.010

Monocytes (cells/mm3)

0.998 [0.995–1.001]

0.180

0.998 [0.995–1.001]

0.212

0.999 [0.996–1.002]

0.463

Neutrophils (cells/mm3)

1.000 [1.000–1.000]

0.262

1.000 [1.000–1.000]

0.326

1.000 [1.000–1.000]

0.239

Viral RNAemia (Yes)

3.916 [1.183–12.968]

0.025

–

–

–

–

Viral RNA load (N1)

in plasma, log (copies/mL)

–

–

1.962 [1.244–3.096]

0.004

–

–

Viral RNA load (N2)

in plasma, log (copies/mL)

–

–

–

–

2.229 [1.382–3.595]

0.001

  1. The association between viral RNAemia or viral RNA load targeting the N1 region, or viral RNA load targeting the N2 region with critical illness was evaluated adjusting by major confounding factors
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Critical Care

ISSN: 1364-8535