Skip to main content

Table 1 Epidemiological and clinical characteristics of patients on an intensive care unit in southwest Germany with and without extracorporeal membrane oxygenation (ECMO) treatment

From: Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study

Characteristic

All patients (n = 105)

Patients on ECMO support (n = 30)

Patients without ECMO support (n = 75)

P

Epidemiology

Male sex

66 (62.9%)

20 (66.7%)

46 (61.3%)

0.661

Age (in years)

57.3 ± 13.9

47.7 ± 13.1

61.2 ± 12.3

 < 0.001

Body mass index (BMI)

27.7 ± 8.3

28.8 ± 10.0

27.2 ± 7.5

0.482

Clinical characteristics

Sequential organ failure assessment (SOFA) score (average score and range)

7.0 (4–9)

7.4 (5–8)

6.0 (4–9)

0.340

ICU mortality

35 (33.3%)

18 (60.0%)

17 (22.7%)

 < 0.001

Median ICU stay until death (in days)

23 (13–36)

32 (22.5–50)

14 (6.75–23.5)

0.001

Continuous renal replacement therapy (CRRT)

Patients requiring CRRT

40 (38.1%)

16 (53.3%)

24 (32.0)

0.048

CRRT blood flow (in ml/min)

101.1 ± 19.6

100.6 ± 18.9

102.8 ± 25.9

0.411

CRRT dialysate flow (in ml/h)

2307.2 ± 536

2486.2 ± 541.6

2101 ± 470.7

 < 0.001

ECMO characteristics

Blood flow (in l/min)

 

3.9 ± 1.1

Duration of ECMO membrane oxygenator use (days)

 

12.6 ± 13.7

  1. Data were obtained during a study on therapeutic drug monitoring of antibiotics, October 2018–December 2019