From: Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDS
Variables | HR | 95% (CI) | p |
---|---|---|---|
Age (year) | 1.04 | 1.003–1.078 | 0.035 |
Sex (female) | 0.006 | 0.000–0.216 | 0.006 |
Fever (days) | 1.001 | 0.912–1.098 | 0.98 |
Pulmonary disease | 1.998 | 0.906–4.408 | 0.086 |
Coronary artery disease | 0.556 | 0,166–1.858 | 0.340 |
Hypertension | 1,767 | 0.706–4.429 | 0.224 |
Diabetes | 1.525 | 0.571–4.072 | 0.40 |
Smokers | 3.050 | 1.313–7.086 | 0.10 |
Obesity | 2.252 | 1.027–4.936 | 0.044 |
Risk factors | – | – | 0.025 |
0 | Ref | – | – |
1 | 6.608 | 0.853–51 | 0.07 |
2 | 5.126 | 0.617–42.6 | 0.13 |
3 | 15.518 | 1.861–129 | 0.011 |
4 | 46.105 | 2.772–766 | 0.008 |
Nasal oxygen | 0.019 | 0.001–0.512 | 0.018 |
Noninvasive ventilation | 0.031 | 0.001–1.386 | 0.073 |
Intubation | 223,89 | 4.81–10,415 | 0.006 |
PaO2/FiO2 ratio (mmHg) | 0.986 | 0.981–0.992 | 0.001 |
Heparin | 0.274 | 0.037–2.039 | 0.206 |
Antivirals | 5.935 | 1.398–25.186 | 0.016 |
Hydroxycloroquine | 1.195 | 0.477–2.995 | 0.704 |
Monoclonal antibody | 3.301 | 1.481–7.356 | 0.003 |
Corticosteroids | 1.308 | 0.521–3.279 | 0.568 |
Creatinine (mg/mL) | 1.236 | 1.067–1.432 | 0.005 |
Troponine (pg/l) | 1.000 | 1.000–1.000 | 0.003 |
D-dimer (ng/ml) | 1.000 | 1.000–1.001 |  < 0.001 |
C-reactive protein (mg/dl) | 1.014 | 1.004–1.024 | 0.006 |
Procalcitonin (ng/ml) | 1.108 | 0.975–1.259 | 0.115 |
NT-proBNP (pg/ml) | 1.000 | 1.000–1.000 |  < 0.001 |
APTT (sec) | 0.997 | 0.982–1.012 | 0.687 |
Interleukine-6 (ng/ml) | 1.010 | 1.007–1.013 |  < 0.001 |
Heart rate (bpm) | 1.031 | 1.006–1.058 | 0.016 |
Systolic blood pressure (mmHg) | 0.976 | 0.949–1.003 | 0.076 |
Diastolic blood pressure (mmHg) | 0.912 | 0.868–0.958 |  < 0.001 |
LVEDd (mm) | 1.031 | 0.948–1.121 | 0.473 |
LVESd (mm) | 1.039 | 0.99–1.091 | 0.123 |
LAD (mm) | 1.066 | 0.995–1.143 | 0.068 |
LVEF (%) | 0.972 | 0.934–1.011 | 0.151 |
Severe MR | 0.526 | 0.071–3.887 | 0.529 |
Severe AR | 0.049 | 0–201,330 | 0.697 |
Severe TR | 2.671 | 0.798–8.95 | 0.111 |
TAPSE (mm) | 0.796 | 0.727–0.871 |  < 0.001 |
PASP (mmHg) | 1.085 | 1.054–1.118 |  < 0.001 |
TAPSE/PASP (mm/mmHg) | 0.013 | 0.002–0.069 |  < 0.001 |
IVC (mm) | 1.335 | 1.201–1.483 |  < 0.001 |
IVC respiratory changes | 1.591 | 0.702–3.606 | 0.226 |
Pericardial effusion | 1.693 | 0.580–4.940 | 0.335 |
Pleural effusion | 0.868 | 0.204–3.689 | 0.848 |
Right phenotype | 4.232 | 1.505–11.902 | 0.006 |