Table 3 Microaspiration indicators and outcomes stratified by VAP incidence within 3 days after TEE
Variables | n | Total (n = 100) | VAP (n = 19) | No VAP (n = 81) | p value |
|---|---|---|---|---|---|
Pre-TEE pepsin (ng/mL) | 82 | 211 (128–379) | 154 (86–337) | 216 (130–380) | 0.49 |
Pre-TEE pepsin > 200 μg/L | 82 | 47 (57.3%) | 7 (46.7%) | 40 (59.7%) | 0.36 |
Post-TEE pepsin (ng/mL) | 83 | 218 (120–329) | 162 (56–368) | 229 (140–323) | 0.37 |
Post-TEE pepsin > 200 μg/L | 83 | 44 (53.0%) | 6 (40.0%) | 38 (55.9%) | 0.26 |
Pre-TEE salivary amylase (IU/L) | 82 | 1932 (454–16700) | 648 (180–2052) | 2792 (568–25220) | 0.10 |
Pre-TEE salivary amylase > 1685 IU/L | 82 | 45 (54.9%) | 6 (40.0%) | 39 (58.2%) | 0.20 |
Post-TEE salivary amylase (IU/L) | 83 | 1532 (632–11820) | 1096 (304–5108) | 1710 (636–11889) | 0.58 |
Post-TEE salivary amylase > 1685 IU/L | 83 | 40 (48.2%) | 5 (33.3%) | 35 (51.5%) | 0.20 |
TEE-associated pepsin absolute variation | 70 | − 5 (− 59 to 32) | − 31 (− 72 to 15) | 0 (− 59 to 35) | 0.42 |
TEE-associated salivary amylase absolute variation | 70 | − 216 (− 2760 to 564) | − 502 (− 1195 to 1095) | − 186 (− 5095 to 468) | 0.86 |
TEE-associated microaspiration | 74 | 17 (23.0%) | 3 (23.1%) | 14 (22.9%) | > 0.99 |
Other outcomes | |||||
Successful extubation | 99 | 62 (62.6%) | 10 (52.6%) | 52 (65.0%) | 0.43 |
MV duration after TEE (d) | 99 | 8 (3–17) | 10(6–18) | 8 (3–17) | 0.37 |
Extubation within three days after TEE | 99 | 26 (26.3%) | 3 (15.8%) | 23 (28.8%) | 0.39 |
MV duration (d) | 99 | 14 (7–27) | 12 (8–33) | 14 (6–27) | 0.70 |
ICU length of stay (d) | 99 | 20 (9–32) | 17 (10–37) | 21 (9–32) | 0.91 |
ICU mortality | 99 | 36 (36.4%) | 8 (42.1%) | 28 (35.0%) | 0.60 |