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Table 3 Diagnostic characteristics (including their 95% confidence interval) of visual readout of the lateral flow assay for the different disease definitions

From: Point of care aspergillus testing in intensive care patients

 

Classification

Sensitivity

Specificity

Negative predictive value

Positive predictive value

All cases

EORTC/MSG (n = 155)

0.81 (0.64–0.93)

0.95 (0.90–0.98)

0.92 (0.85–0.96)

0.88 (0.76–0.94)

 

AspICU

(n = 141)

0.89 (0.65–0.99)

0.95 (0.90–0.98)

0.95 (0.84–0.99)

0.89 (0.78–0.95)

 

modified AspICU

(n = 178)

0.75 (0.61–0.85)

0.95 (0.90–0.98)

0.90 (0.85–0.93)

0.87 (0.75–0.94)

Criteria excluding galactomannan

EORTC/MSG (n = 140)

0.94 (0.71–1.00)

0.95 (0.90–0.98)

0.97 (0.85–1.00)

0.89 (0.79–0.95)

Modified AspICU (n = 152)

0.86 (0.68–0.96)

0.95 (0.90–0.98)

0.94 (0.87–0.98)

0.88 (0.77–0.94)