Table 2 Diagnostic characteristics (including their 95% confidence interval) of digital readout of the lateral flow assay for the different disease definitions
From: Point of care aspergillus testing in intensive care patients
Classification | Sensitivity | Specificity | Negative predictive value | Positive predictive value | |
|---|---|---|---|---|---|
All Cases | EORTC/MSG (n = 155) | 0.88 (0.71–0.96) | 0.81 (0.73–0.88) | 0.94 (0.86–0.97) | 0.67 (0.58–0.75) |
AspICU (n = 141) | 0.94 (0.73–1.00) | 0.81 (0.73–0.88) | 0.97 (0.84–1.00) | 0.68 (0.60–0.76) | |
modified AspICU (n = 178) | 0.87 (0.76–0.95) | 0.81 (0.73–0.88) | 0.94 (0.88–0.97) | 0.67 (0.58–0.75) | |
Criteria excluding galactomannan | EORTC/MSG (n = 140) | 1.00 (0.80–1.00) | 0.81 (0.73–0.88) | 0.96 (0.84–0.99) | 0.67 (0.58–0.74) |
modified AspICU (n = 152) | 0.97 (0.82–1.00) | 0.81 (0.73–0.88) | 0.98 (0.89–1.00) | 0.69 (0.60–0.76) |