Skip to main content

Table 2 Muscle ultrasound, strength, power and physical function

From: Acute skeletal muscle wasting and dysfunction predict physical disability at hospital discharge in patients with critical illness

Muscle parameter

Day 1

Day 7

Ultrasound parameters

n = 41

n = 41

 TA mT (cm)

2.01 (0.36)

1.82 (0.31)

 TA CSA (cmPP2PP)

5.28 (0.89)

4.71 (0.95)

 TA EI (0–255)

82.7 (21.2)

96.7 (22.6)

 RF mT (cm)

0.98 (0.3)

0.81 (0.27)

 RF + VI mT (cm)

2.04 (0.71)

1.77 (0.62)

 RF CSA (cmPP2PP)

2.99 (0.99)

2.47 (0.88)

 RF EI (0–255)

90.7 (24.9)

99.1 (27.6)

 

ICU discharge

Hospital discharge

Muscle power (W)

n = 26a

n = 33b

 2 lbs

8.0 (2.89)

9.6 (3.5)

 10% bodyweight

44.8 (22.6)

58.7 (30.6)

Muscle strength

 MRC-ss (0–60)

47.1 (7.3) (n = 31)c

51.4 (5.7) (n = 35)e

 RF HHD force (kg)

16.9 (5.3) (n = 24)d

19.8 (6.9) (n = 31)f

 RF HHD RFD (seconds)

3.8 (1.1) (n = 24)d

3.6 (1.1) (n = 31)f

 TA HHD (kg)

14.5 (5.2) (n = 24)d

15.6 (5.4) (n = 31)f

 TA HHD RFD (seconds)

3.9 (1.2) (n = 24)d

3.7 (1.2) (n = 31)f

 Handgrip (kg)

18.2 (9.1) (n = 26)a

21.7 (10.0) (n = 32)g

Physical function

 SPPB

4.7 (3.9) (n = 26)a

5.9 (4.0) (n = 35)e

 4-m gait speed (m/s)

0.49 (0.18) (n = 19)h

0.56 (0.27) (n = 31)f

 5 × STS (seconds)

14.8 (5.6) (n = 13)i

18.9 (14.5) (n = 28)j

 Balance

1.96 (1.4) (n = 19)h

2.3 (1.2) (n = 31)f

 6 MWT distance (feet)

265 (182) (n = 26)a

455 (424) (n = 35)e

CFS

6.1 (1.5) (n = 36)

5.3 (1.7) (n = 36)

  1. TA = tibialis anterior muscle; RF = rectus femoris muscle; CSA = cross-sectional area, mT = muscle layer thickness; EI = echointensity; MRC-ss = Medical Research Council-sum score; VI = vastus intermedius muscle; HHD = handheld dynamometer; RFD = rate of force development; SPPB = short performance physical battery; 5 × STS = five-times sit-to-stand test; 6 MWT = six-minute walk test; W = watts; CFS = clinical frailty scale
  2. aTen patients unable to complete test: 4 patients unable to follow commands/poor cognition; 3 patients had < 3/5 strength; 2 were missed by assessor; and 1 patient was unable to maintain oxygen saturations > 10% of baseline with simple movement in bed;
  3. bThree unable to complete: 2 patients with < 3/5 strength and 1 patient unable to complete test: missed by assessor
  4. cFive patients unable to complete: 4 patients unable to follow commands/poor cognition, 1 patient declined due to pain
  5. dTwelve patients unable to complete test: patients reported in footnote b plus 2 patients fatigued after initial testing and physically were unable to perform HHD testing
  6. eOne patient declined due to pain
  7. fFive patients unable to complete: 2 with < 3/5 strength, 2 deferred to pain/fatigue, 1 patient missed by assessor
  8. gFour patients unable to complete: 2 with < 3/5 strength, 1 deferred to pain/fatigue, 1 patient missed by assessor
  9. hSeventeen patients unable to complete test: patients reported in footnote b plus 7 patients unable to stand for balance or walk 4 m without physical assistance
  10. iTwenty-three patients unable to complete test: patients reported in footnote b plus 13 patients unable to stand from chair in time allotted or without assistance
  11. jEight patients unable to complete: 2 with < 3/5 strength, 2 deferred to pain/fatigue, 1 patient missed by assessor, 3 patients could not perform without assistance