Skip to main content

Table 3 Odds ratios for bio-ADM from multivariable binary logistic regression analyses for different outcomes

From: Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness

Outcome

ICU population

Sepsis cohort

OR

95% CI

p value

OR

95% CI

p value

30-day mortality

1.22

1.12–1.32

< 0.001

1.23

1.07–1.41

0.003

30-day mortality†

N/A

N/A

N/A

1.20

1.04–1.38

0.010

Cardiovascular SOFA\(\ge\) 3

1.33

1.23–1.42

< 0.001

1.33

1.17–1.50

< 0.001

CRRT use during ICU stay

2.28

2.01–2.59

< 0.001

1.97

1.64–2.36

< 0.001

Sepsis

1.91‡

1.76–2.08‡

< 0.001‡‡

N/A

N/A

N/A

Sepsis*

1.78‡

1.64–1.94‡

< 0.001‡

N/A

N/A

N/A

Septic shock

1.95

1.76–2.16

< 0.001

1.45

1.28–1.65

< 0.001

Septic shock*

1.78‡

1.60–1.98‡

< 0.001‡

1.35

1.19–1.54

< 0.001

  1. The odds ratio for bio-ADM was calculated on a base 2 logarithmic scale. Age was included as a covariate in all regressions not including simplified acute physiology score III (SAPS3), as this is already an integral part of SAPS3. An additional covariate for the † model was lactate, and for the * models, the SAPS3 was included. If the Hosmer–Lemeshow test was \(p<\) 0.05, the model was marked ‡. ICU: intensive care unit; OR: odds ratio; CI: confidence interval; SOFA: Sequential Organ Failure Assessment; CRRT: continuous renal replacement therapy; N/A: not applicable
Back to article page

Critical Care

ISSN: 1364-8535