Table 1 Baseline characteristics of all patients divided by intervention and acuity of illness at ICU admission
Control group | Intervention group | ||||||
|---|---|---|---|---|---|---|---|
Low acuity of illness (APACHE II score ≤ 13) | Moderate acuity of illness (APACHE II score 14–20) | High acuity of illness (APACHE II score ≥ 21) | Low acuity of illness (APACHE II score ≤ 13) | Moderate acuity of illness (APACHE II score 14–20) | High acuity of illness (APACHE II score ≥ 21) | p for interaction | |
n = 36 | n = 29 | n = 31 | n = 38 | n = 34 | n = 32 | ||
Age—median [IQR] | 57 [34, 68] | 64 [46, 77] | 66 [56, 79] | 52 [39, 67] | 67 [51, 74] | 67 [60, 75] | 0.113 |
Female gender—n (%) | 15 (42) | 10 (34) | 10 (32) | 17 (45) | 11 (32) | 11 (34) | 0.716 |
GCS—median [IQR] | 10.0 [9.0, 11.5] | 9.0 [8.0, 10.0] | 9.0 [6.0, 10.0] | 10.0 [9.0, 12.0] | 9.0 [8.0, 10.0] | 8.50 [5.5, 9.5] | 0.927 |
APACHE II—median [IQR] | 10.0 [7.0, 12.0] | 17.0 [16.0, 19.0] | 25.0 [22.0, 28.0] | 10.5 [8.0, 12.0] | 17.0 [15.0, 19.0] | 26.0 [22.0, 29.0] | 0.048 |
Charlson Comorbidity Index—mean ± SD | 1.69 ± 2.20 | 3.16 ± 3.60 | 3.10 ± 2.85 | 2.55 ± 4.15 | 2.22 ± 2.60 | 3.79 ± 3.13 | 0.546 |
Comorbidities | |||||||
Myocardial infarction—n (%) | 1 (3) | 4 (14) | 4 (13) | 3 (8) | 1 (3) | 2 (6) | 0.223 |
Cerebrovascular disease—n (%) | 6 (17) | 7 (24) | 4 (13) | 4 (11) | 3 (9) | 2 (6) | 0.406 |
Diabetes mellitus—n (%) | 2 (6) | 8 (28) | 7 (23) | 3 (8) | 4 (12) | 9 (28) | 0.457 |
Hemiplegia or paraplegia—n (%) | 3 (8) | 0 (0) | 0 (0) | 3 (8) | 0 (0) | 2 (6) | 0.826 |
Surgery classification | |||||||
Abscess drainage—n (%) | 5 (14) | 0 (0) | 0 (0) | 3 (8) | 3 (9) | 0 (0) | 0.723 |
Damage control surgery—n (%) | 8 (22) | 4 (14) | 3 (10) | 5 (13) | 6 (18) | 3 (9) | 0.233 |
Aneurysm repair—n (%) | 6 (17) | 3 (10) | 3 (10) | 3 (8) | 7 (20) | 6 (19) | 0.364 |
General surgery | 2 (6) | 3 (10) | 10 (32) | 7 (18) | 5 (15) | 8 (25) | 0.096 |
Neurosurgery—n (%) | 5 (14) | 4 (14) | 0 (0) | 6 (16) | 0 (0) | 0 (0) | 0.638 |
Other—n (%) | 10 (27) | 15 (51) | 15 (48) | 14 (37) | 13 (38) | 15 (46) | 0.306 |