|
Age, year
|
65.0 [56.0;74.5]
|
65.0 [55.5;74.5]
|
67.0 [59.0;77.0]
|
0.203
|
|
Weight
|
74.0 [66.5;83.0]
|
70.0 [59.5;80.0]
|
79.0 [69.5;90.0]
|
< 0.001
|
|
Height
|
172.0 [165.0;176.0]
|
170.0 [165.0;175.0]
|
170.0 [162.0;175.0]
|
0.294
|
|
Body mass index
|
24.9 [22.5;29.1]
|
24.5 [20.8;26.1]
|
27.8 [23.8;31.9]
|
< 0.001
|
|
SAPS2
|
55.0 [41.0;67.5]
|
57.0 [40.0;66.5]
|
59.0 [47.0;72.0]
|
0.113
|
|
SOFA score
|
10.0 [8.0;12.0]
|
9.0 [6.0;11.5]
|
10.0 [8.0;12.0]
|
0.527
|
|
Hemodynamic parameters
| | | | |
|
Heart rate, bpm
|
108.5 [88.0;126.0]
|
105.0 [90.0;130.0]
|
103.0 [86.0;116.0]
|
0.056
|
|
Systolic arterial blood pressure, mmHg
|
120.0 [105.0;133.0]
|
96.0 [86.0;113.5]
|
108.5 [91.0;124.5]
|
< 0.001
|
|
Diastolic arterial blood pressure, mmHg
|
65.0 [55.5;74.0]
|
53.0 [47.0;63.5]
|
58.0 [51.0;68.0]
|
< 0.001
|
|
Mean arterial blood pressure, mmHg
|
82.0 [72.5;94.0]
|
70.0 [61.0;82.0]
|
74.0 [65.5;85.0]
|
< 0.001
|
|
Pulse pressure variation, %
|
9.0 [5.0;14.5]
|
13.0 [5.0;20.0]
|
8.0 [4.0;13.0]
|
0.127
|
|
Central venous pressure, mmHg
|
9.0 [7.0;12.0]
|
5.0 [3.0; 6.5]
|
12.0 [10.0;14.5]
|
0.000
|
|
Fluid expansion volume before echo, mL
|
2000.0 [1000.0;3696.5]
|
2000.0 [1427.5;4000.0]
|
2000.0 [1000.0;3500.0]
|
0.700
|
|
Arterial blood lactate level, mmol/L
|
2.3 [1.5; 4.0]
|
2.3 [1.4; 4.2]
|
2.2 [1.4; 3.8]
|
0.775
|
|
IAP, mmHg
|
10.0 [7.5;15.0]
|
8.5 [5.0;10.0]
|
11.0 [8.0;14.0]
|
0.002
|
|
Epinephrine
|
4 (4.0%)
|
2 (4.8%)
|
7 (7.1%)
|
0.619
|
|
Epinephrine dose, mg/h
|
0.9 [0.6; 1.1]
|
1.5 [1.0; 2.0]
|
2.0 [1.4; 2.6]
|
0.030
|
|
Norepinephrine
|
98 (98.0%)
|
40 (95.2%)
|
94 (94.9%)
|
0.487
|
|
Norepinephrine dose, mg/h
|
1.8 [1.0; 3.6]
|
1.9 [1.0; 2.8]
|
1.6 [0.8; 2.9]
|
0.655
|
|
Dobutamine
|
7 (7.0%)
|
6 (14.3%)
|
11 (11.1%)
|
0.368
|
|
Dobutamine dose, µg/kg/min
|
5.0 [5.0; 6.5]
|
5.0 [2.5; 5.0]
|
5.0 [2.5; 6.0]
|
0.637
|
|
Echo parameters
| | | | |
|
Atrial fibrillation at the time of echo
|
17 (14.8)
|
5 (10.6)
|
25 (20.8)
|
0.247
|
|
E/A ratio
|
0.9 [0.7; 1.3]
|
0.9 [0.7; 1.2]
|
0.8 [0.7; 1.2]
|
0.630
|
|
Superior vena cava collapsibility, %
|
11.8 [5.3;25.0]
|
15.8 [6.3;28.6]
|
10.0 [5.0;25.8]
|
0.417
|
|
Inferior vena cava distensibility, %
|
5.3 [0.0;11.1]
|
5.9 [0.0;12.5]
|
4.5 [0.0; 9.5]
|
0.637
|
|
LVEF, %
|
51.0 [39.0;63.0]
|
53.0 [41.5;60.0]
|
51.0 [38.0;63.5]
|
0.995
|
|
RV/LV end-diastolic area
|
0.5 [0.4; 0.5]
|
0.7 [0.7; 0.9]
|
0.7 [0.7; 0.9]
|
0.000
|
|
Paradoxical septal motion
|
2 (1.7%)
|
4 (8.5%)
|
17 (14.2%)
|
0.001
|
|
Systolic pulmonary artery pressure, mmHg
|
41.0 [36.0;48.0]
|
38.5 [33.0;43.0]
|
45.0 [39.0;52.0]
|
0.016
|
|
CI, L/min/m2
|
3.8 [2.9;4.6]
|
3.8 [3.0;4.4]
|
3.4 [2.8;4.1]
|
0.392
|
|
TAPSE, mm
|
18.0 [15.0;22.0]
|
18.0 [15.0;21.0]
|
18.0 [14.0;21.0]
|
0.298
|
|
Fluid expansion after echo
|
50 (43.5%)
|
28 (59.6%)
|
37 (30.8%)
|
0.002
|
|
Aortic VTI, cm
|
19.4 [16.4;22.1]
|
16.8 [15.2;19.9]
|
20.0 [15.6;23.3]
|
0.185
|
