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Table 1 Baseline characteristics according to RV/LV EDA and CVP. Group 3 included patients suspected to have RV failure

From: Right ventricular failure in septic shock: characterization, incidence and impact on fluid responsiveness

  Group 1 (N = 115) Group 2 (N = 47) Group 3 (N = 120) p value
Age, year 65.0 [56.0;74.5] 65.0 [55.5;74.5] 67.0 [59.0;77.0] 0.203
Weight 74.0 [66.5;83.0] 70.0 [59.5;80.0] 79.0 [69.5;90.0] < 0.001
Height 172.0 [165.0;176.0] 170.0 [165.0;175.0] 170.0 [162.0;175.0] 0.294
Body mass index 24.9 [22.5;29.1] 24.5 [20.8;26.1] 27.8 [23.8;31.9] < 0.001
SAPS2 55.0 [41.0;67.5] 57.0 [40.0;66.5] 59.0 [47.0;72.0] 0.113
SOFA score 10.0 [8.0;12.0] 9.0 [6.0;11.5] 10.0 [8.0;12.0] 0.527
Hemodynamic parameters     
Heart rate, bpm 108.5 [88.0;126.0] 105.0 [90.0;130.0] 103.0 [86.0;116.0] 0.056
Systolic arterial blood pressure, mmHg 120.0 [105.0;133.0] 96.0 [86.0;113.5] 108.5 [91.0;124.5] < 0.001
Diastolic arterial blood pressure, mmHg 65.0 [55.5;74.0] 53.0 [47.0;63.5] 58.0 [51.0;68.0] < 0.001
Mean arterial blood pressure, mmHg 82.0 [72.5;94.0] 70.0 [61.0;82.0] 74.0 [65.5;85.0] < 0.001
Pulse pressure variation, % 9.0 [5.0;14.5] 13.0 [5.0;20.0] 8.0 [4.0;13.0] 0.127
Central venous pressure, mmHg 9.0 [7.0;12.0] 5.0 [3.0; 6.5] 12.0 [10.0;14.5] 0.000
Fluid expansion volume before echo, mL 2000.0 [1000.0;3696.5] 2000.0 [1427.5;4000.0] 2000.0 [1000.0;3500.0] 0.700
Arterial blood lactate level, mmol/L 2.3 [1.5; 4.0] 2.3 [1.4; 4.2] 2.2 [1.4; 3.8] 0.775
IAP, mmHg 10.0 [7.5;15.0] 8.5 [5.0;10.0] 11.0 [8.0;14.0] 0.002
Epinephrine 4 (4.0%) 2 (4.8%) 7 (7.1%) 0.619
Epinephrine dose, mg/h 0.9 [0.6; 1.1] 1.5 [1.0; 2.0] 2.0 [1.4; 2.6] 0.030
Norepinephrine 98 (98.0%) 40 (95.2%) 94 (94.9%) 0.487
Norepinephrine dose, mg/h 1.8 [1.0; 3.6] 1.9 [1.0; 2.8] 1.6 [0.8; 2.9] 0.655
Dobutamine 7 (7.0%) 6 (14.3%) 11 (11.1%) 0.368
Dobutamine dose, µg/kg/min 5.0 [5.0; 6.5] 5.0 [2.5; 5.0] 5.0 [2.5; 6.0] 0.637
Echo parameters     
Atrial fibrillation at the time of echo 17 (14.8) 5 (10.6) 25 (20.8) 0.247
E/A ratio 0.9 [0.7; 1.3] 0.9 [0.7; 1.2] 0.8 [0.7; 1.2] 0.630
Superior vena cava collapsibility, % 11.8 [5.3;25.0] 15.8 [6.3;28.6] 10.0 [5.0;25.8] 0.417
Inferior vena cava distensibility, % 5.3 [0.0;11.1] 5.9 [0.0;12.5] 4.5 [0.0; 9.5] 0.637
LVEF, % 51.0 [39.0;63.0] 53.0 [41.5;60.0] 51.0 [38.0;63.5] 0.995
RV/LV end-diastolic area 0.5 [0.4; 0.5] 0.7 [0.7; 0.9] 0.7 [0.7; 0.9] 0.000
Paradoxical septal motion 2 (1.7%) 4 (8.5%) 17 (14.2%) 0.001
Systolic pulmonary artery pressure, mmHg 41.0 [36.0;48.0] 38.5 [33.0;43.0] 45.0 [39.0;52.0] 0.016
CI, L/min/m2 3.8 [2.9;4.6] 3.8 [3.0;4.4] 3.4 [2.8;4.1] 0.392
TAPSE, mm 18.0 [15.0;22.0] 18.0 [15.0;21.0] 18.0 [14.0;21.0] 0.298
Fluid expansion after echo 50 (43.5%) 28 (59.6%) 37 (30.8%) 0.002
Aortic VTI, cm 19.4 [16.4;22.1] 16.8 [15.2;19.9] 20.0 [15.6;23.3] 0.185
  1. Continuous variables are presented as the median [interquartile], while categorical variables are presented as n (%)