Skip to main content

Table 2 Effects of increasing NHF set flow rate on target physiologic variables

From: Nasal high flow higher than 60 L/min in patients with acute hypoxemic respiratory failure: a physiological study

  NHF-0.5 NHF-1 NHF-1.5 ANOVA p value
Set flow rate (L/min) 35 (30–35) 65 (60–70)a 100 (92–109)a,b  < 0.001
PaO2/FiO2 194 ± 96 211 ± 106 219 ± 118 0.064
SpO2 (%) 94 ± 2 95 ± 2 96 ± 2 0.139
Arterial pH 7.40 (7.39–7.43) 7.40 (7.39–7.41) 7.41 (7.40–7.45) 0.105
PaCO2 ( mmHg) 36.3 ± 6.4 37.6 ± 5.3 36.2 ± 5.7 0.108
RR (bpm) 20 ± 6c 17 ± 5 18 ± 6 0.014
Corrected MV (au/min) 46,440 ± 18,515 48,562 ± 17,781 53,870 ± 17,737 0.068
HR (bpm) 78 ± 16 76 ± 17 77 ± 16 0.391
MAP (mmHg) 76 (62–91) 73 (65–80) 74 (61–89) 0.447
  1. NHF, nasal high flow; 0.5-1-1.5, set flow rate in L/kg PBW/min; PaO2/FiO2, arterial partial pressure of O2/inspired fraction of O2 ratio; SpO2, peripheral oxygen saturation; PaCO2, arterial partial pressure of CO2; RR, respiratory rate; HR, heart rate; MAP, mean arterial pressure
  2. aPost hoc Dunn’s test versus NHF-0.5 (p < 0.05)
  3. bPost hoc Dunn’s test versus NHF-1 (p < 0.05)
  4. cPost hoc Bonferroni test versus NHF-1 (p < 0.05)