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Table 2 Administration of corticosteroids, stratified by outcome

From: Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis

 

All (n = 226)

Non-survivors (n = 135)

Survivors (n = 91)

p value

Corticosteroid prescribed

 Methylprednisolone

213 (94.2)

132 (62.0)

83 (38.0)

0.0004

 Prednisolone

41 (18.1)

11 (73.2)

30 (26.8)

0.0007

 Dexamethasone

5 (2.2)

4 (80.0)

1 (20.0)

0.4470

Maximum dose (methylprednisolone equivalent, mg)

80.0 (40.0–80.0)

80.0 (40.0–80.0)

80.0 (40.0–80.0)

0.0821

Days of corticosteroid treatment

7.0 (4.0–12.0)

6.0 (3.0–11.0)

9.0 (5.0–12.0)

0.0069

Days of maximum dose

3.0 (2.0–5.0)

3.0 (1.0–5.0)

4.0 (2.0–5.0)

0.0287

Days from symptom onset to corticosteroid treatment

13.0 (10.0–16.0)

14.0 (11.0–18.0)

11.0 (9.0–14.0)

0.0031

Days from hospital admission to corticosteroid treatment

1.0 (0.0–3.0)

1.0 (0.0–4.0)

1.0 (0.0–2.0)

0.1892

Days from ARDS to corticosteroid treatment

0.0 (0.0–2.0)

1.0 (0.0–2.0)

0.0 (− 1.0 to 1.0)

0.0102

Days from ventilation to corticosteroid treatment

− 1.0 (− 3.0 to 0.0)

− 1.0 (− 3.0 to 0.0)

− 2.0 (− 4.0 to 1.0)

0.7576

  1. Data are n (%) or medium (IQR). For continuous variables, t test or Mann–Whitney U test was used to calculate the p value unless otherwise noted. For categorical variables, chi-square test was used to calculate the p value unless otherwise noted