Fig. 2.

51-year-old male patient, RT-PCR confirmed COVID-19, 3 days since symptom onset. Admission PaO₂/FiO₂ ratio was 240, and d-dimer level was 480 ng/mL. Admitted to the intensive care unit, managed with invasive mechanical ventilation. a Axial lung-window CT angiography image shows extensive bilateral ground-glass opacities, with areas of posterior subpleural consolidation. There is subtle subsegmental peripheral vascular dilatation of pulmonary arterial branches (small black arrows). b 5 mm axial reconstruction of a subtraction iodine map shows slight to moderate hypoperfusion predominantly in areas of non-injured lung (*), and more prominent areas of increased perfusion in relation to the zones of ground-glass opacities (white arrows). Perfusion was not assessed in the areas of consolidation (black arrows) due to software limitations that exclude these zones. This patient evolved in a similar fashion to the H (type 2) phenotype described by Gattinoni et al.