Skip to main content
Fig. 2 | Critical Care

Fig. 2

From: Gut-liver crosstalk in sepsis-induced liver injury

Fig. 2

Effect of cytokines on the gut barrier during sepsis. During sepsis, increased levels of cytokines can modulate gut permeability by regulating the protein expression of claudins, JAM-A, occludin, and ZO-1. The phosphorylation of myosin regulatory light chain by myosin light chain kinase (MLCK) can increase paracellular permeability and result in contraction or opening of the apical tight junctions

Back to article page

Critical Care

ISSN: 1364-8535