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Table 1 Characteristics of laboratory animals before the start of the experiment

From: Individualized flow-controlled ventilation compared to best clinical practice pressure-controlled ventilation: a prospective randomized porcine study

  Total (n = 12) FCV (n = 6) PCV (n = 6) MD with 95% CIa p valueb
Demographic data
 Weight kg 37.8 (33.8–43.3) 36.2 (32.9–38.7) 40.5 (36.6–44.8) − 4.1 (− 11.6 to 2.3) 0.240
 Size m 1.08 (1.07–1.10) 1.08 (1.06–1.10) 1.08 (1.07–1.14) −0.03 (− 0.09 to 0.03) 0.511
 Gender female 7/12 (58.3%) 4/6 (66.7%) 3/6 (50%) 0.53 (0.03 to 8.30) 1
Monitoring data
 HR /min 89.0 (81.0–95.5) 91.0 (84.0–94.3) 85.0 (76.8–94.8) 3.9 (−8.0 to 20.0) 0.521
 MAP mm Hg 65.5 (63.0–72.0) 73.0 (66.5–75.75) 63.0 (63.0–65.3) 8.0 (−4.0 to 15.0) 0.106
 MPAP mm Hg 22.0 (20.0–23.3) 21.0 (20.3–24.8) 23.0 (20.8–23.0) −0.5 (−4.0 to 8.0) 1
 CVP mm Hg 10.0 (8.0–13.0) 9.0 (8.0–10.0) 13.0 (10.8–13.0) −3.0 (−6.0 to 6.0) 0.220
 CI l/min/m2 6.1 (5.7–6.6) 6.0 (5.6–6.4) 6.2 (5.9–7.5) −0.4 (− 2.2 to 0.7) 0.485
 PCWP mmHg 11.0 (9.0–13.0) 10.0 (6.0–11.0) 12.5 (11.3–13.0) −3.0 (−8.0 to 2.0) 0.195
VT ml/kg 7.1 (7.1–7.5) 7.2 (7.1–7.7) 7.1 (7.0–7.3) 0.1 (−0.3 to 0.9) 0.191
 RR /min 35.0 (33.8–37.3) 34.0 (31.0–36.3) 36..0 (34.5–37.5) −2.0 (−8.0 to 2.0) 0.332
 MV l/min 9.5 (9.0–11.6) 9.1 (8.9–9.4) 11.6 (10.1–11.8) −2.4 (−4.3 to −0.1) 0.041*
Ppeak cm H2O 19.5 (18.0–22.5) 18.5 (18.0–19.8) 23.0 (19.0–27.0) −4.0 (−10.0 to 1.0) 0.195
 ΔP cm H2O 14.5 (13.0–17.5) 13.5 (13.0–14.8) 18.0 (14.0–22.0) −4.0 (−10.0 to 1.0) 0.195
Pes cm H2O 12.0 (12.0–15.0) 12.0 (12.0–15.0) 12.5 (12.0–14.5) 0.0 (− 4.0 to 3.0) 0.924
 paCO2 Torr 41.1 (39.3–43.3) 40.4 (39.0–42.8) 41.8 (40.0–42.9) −0.9 (−4.6 to 2.5) 0.699
kPa 5.47 (5.24–5.77) 5.38 (5.20–5.70) 5.57 (5.33–57.20) −0.12 (− 0.61 to 0.33)  
 paO2 Torr 120.5 (97.8–127.3) 113.5 (99.8–123.5) 123.0 (95.8–130.8) −4.5 (−30.0 to 34.0) 0.818
kPa 16.07 (13.03–16.97) 15.13 (13.30–16.47) 16.40 (12.77–17.43) −0.60 (−4.00 to 4.53)  
  1. CI cardiac index, CVP central venous pressure, FCV flow-controlled ventilation, HR heart rate, MAP mean arterial pressure, MD mean difference, MPAP mean pulmonary arterial pressure, MV respiratory minute volume, paCO2 arterial partial pressure of carbon dioxide, paO2 arterial partial pressure of oxygen, PCV pressure-controlled ventilation, PCWP pulmonary capillary wedge pressure, Pes esophageal pressure, Ppeak peak pressure, RR respiratory rate, VT tidal volume, ΔP driving pressure (difference between positive end-expiratory pressure and peak pressure);
  2. Binary data are presented as no./total no. (%), continuous data as medians (25th to 75th percentile)
  3. aOdds ratios for binary variables and estimated median difference for continuous variables
  4. bAssessed by Fisher’s exact test for categorical variables and Wilcoxon rank sum test for continuous variables