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Table 4 Baseline levels and overtime variations in IL-6 and SOFA score in patients treated with tocilizumab and/or lopinavir-ritornavir

From: Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot study

 

n (%)

Baseline SOFA score

Baseline IL-6

Δ SOFA score at 24 h

Δ IL-6 at 24 h

Mortality rate

Tocilizumab

 

15 (40.5%)

13 (IQR 3.5)

1598 (IQR 1635)*

− 1 (IQR − 2.3)

− 642 (IQR − 548)

8 (53.3%)

Lop_Rit

2 (5.4%)

13 (IQR 2)

1125 (IQR 275)

− 4.00 (IQR 0)§

− 571 (IQR −71)

1 (50.0%)

No-Lop_Rit

13 (35.1%)

13 (IQR 3)

1753 (IQR 1933)

− 0.50 (IQR − 1)§

− 904 (IQR − 631)

7 (53.8%)

No-Tocilizumab

 

22 (59.5%)

13 (IQR 7.8)

1089 (IQR 67)*

0 (IQR − 1)

− 552 (IQR − 526)

13 (59.1%)

Lop_Rit

7 (18.9%)

14 (IQR 5.5)

1180 (IQR 80)

− 1 (IQR − 2)

− 702 (IQR − 15)

3 (42.9%)

No-Lop_Rit

15 (40.5%)

13 (IQR 8.5)

794 (IQR 607)

0 (IQR − 1)

− 401 (IQR − 601)

10 (66.7%)

  1. (Lop_Rit). *p = 0.02, §p = 0.049