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Fig. 3 | Critical Care

Fig. 3

From: Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice

Fig. 3

Outcomes of lung infection by P. aeruginosa. a, b Lung and spleen bacterial loads and c alveolar-capillary barrier permeability measured 24-h after intra-nasal sublethal P. aeruginosa (PAO1), in mice previously treated or not (controls) with 7-day oral vancomycin/colistin (VAN/CST) followed by fecal microbiota transplant (VAN/CST + FMT) or not. d 72-h survival of mice challenged with sublethal P. aeruginosa (PAO1) treated or not (controls) with 7-day oral vancomycin/colistin (VAN/CST) followed by fecal microbiota transplant (VAN/CST + FMT) or not. For all experiments, there are 5 mice per group, except for mortality, and 10 mice per group in duplicate; results are shown as mean ± SD; *p < 0.05

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