Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

Table 3 Correlations between cytokines, leukocyte response, and changes in hemoglobin, lactate, and organ function variables

Variable	Log IL-6_3h	Log IL-10_1h	Leukocytes, 3–0 h	Hemoglobin, 3–0 h	LVSWI, 3–0 h	Lactate, 3–0 h	Platelets, 3–0 h	Stat. pulm. Compl., 3–0 h	PaO₂/FiO₂, 3–0 h	Creatinine, 3–0 h
Log TNF-α_1h	0.87***	0.71**	− 0.79***	0.32	− 0.57*	0.88***	− 0.63**	− 0.19	− 0.62*	0.44
Log IL-6_3h	–	0.47	− 0.71**	0.34	− 0.61*	0.77***	− 0.65**	− 0.29	− 0.78***	0.39
Log IL-10_1h	–	–	− 0.63**	0.14	− 0.27	0.55*	− 0.11	− 0.24	− 0.43	− 0.05
Leukocytes_3-0h	–	–	–	− 0.40	0.34	− 0.70**	0.38	0.49	0.77***	− 0.07

LVSWI left ventricular stroke work index, Stat. pulm. Compl. static pulmonary compliance
Pearson’s correlation test was used, except in the correlations for creatinine in which Spearman’s rank correlation test was calculated
*p < 0.05; **p < 0.01; ***p < 0.001

ISSN: 1364-8535