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Table 2 Effect of glucocorticoid on the outcome and inflammatory response on discharge of COVID-19 patients

From: Glucocorticoid therapy does not delay viral clearance in COVID-19 patients

Variables Mild and general group Severe and critical group
Non-GC group GC group p value Non-GC group GC group p value
N 460 30   108 72  
Hospital stay (days) 23.00 [16.00, 33.00] 32.50 [23.25, 38.00] 0.002 29.00 [17.00, 44.00] 40.50 [31.75, 52.50] < 0.001
Viral RNA clearance (days) 22.00 [11.00, 35.00] 23.50 [14.00, 34.25] 0.737 25.50 [13.00, 39.00] 26.00 [17.00, 42.00] 0.471
Total course (days) 43.00 [29.00, 57.00] 41.00 [31.50, 47.75] 0.816 49.00 [37.50, 63.50] 49.00 [43.00, 63.00] 0.341
Outcome (%)    1    0.555
 Survival 446 (99.8) 30 (100.0)   92 (90.2) 62 (86.1)  
 Death 1 (0.2) 0 (0.0)   10 (9.8) 10 (13.9)  
Inflammatory response, median (IQR)
 CRP (mg/L) 2.93 [0.90, 10.00] 4.15 [2.04, 10.50] 0.378 3.19 [0.77, 21.20] 4.59 [1.16, 13.15] 0.457
 IL-6 (pg/mL) 3.00 [2.00, 7.00] 5.00 [2.00, 12.50] 0.253 16.00 [4.75, 36.00] 9.50 [7.25, 32.00] 0.986
 Fib (g/L) 3.58 [2.78, 4.84] 3.96 [3.58, 11.43] 0.227 3.53 [2.84, 14.39] 3.90 [3.60, 10.90] 0.275
 WBC (109/L) 5.55 [4.40, 6.55] 5.20 [4.25, 6.08] 0.568 5.93 [5.00, 7.50] 6.80 [4.90, 8.55] 0.485
 Neutrophil (109/L) 3.17 [2.49, 4.04] 3.05 [2.25, 3.98] 0.641 3.76 [2.85, 5.20] 4.79 [3.09, 6.80] 0.178
 Monocyte (109/L) 0.46 [0.36, 0.57] 0.49 [0.41, 0.66] 0.177 0.43 [0.35, 0.66] 0.51 [0.40, 0.63] 0.311
 Lymphocyte (109/L) 1.56 [1.25, 1.91] 1.47 [1.23, 1.88] 0.801 1.21 [0.97, 1.79] 1.10 [0.85, 1.55] 0.207
 PLT (109/L) 209.0 [173.0, 258.0] 212.0 [183.8, 266.5] 0.923 212.0 [151.0, 236.0] 183.0 [144.0, 250.0] 0.615
 Hb (g/L) 128.5 [117.25, 138.8] 133.0 [127.0, 137.0] 0.667 117.5 [102.5, 129.0] 119.0 [100.0, 125.0] 0.669
 CD3 (count/μL) 1144 [861, 1293] 1002 [793, 1282] 0.791 509 [162.0, 1026] 683.5 [478.8, 1112] 0.508
 CD4 (count/μL) 625.0 [514.0, 831.5] 498.0 [385.0, 801.0] 0.442 306.0 [65.3, 585.5] 338.5 [257.5, 547.0] 0.449
 CD8 (count/μL) 357.0 [246.0, 454.0] 364.0 [248.5, 478.5] 0.845 133.0 [72.3, 341.5] 257.0 [190.3, 389.3] 0.257
 NK (count/μL) 201.0 [128.0, 271.5] 90.0 [55.0, 132.0] 0.008 52.5 [40.0, 124.00] 93.50 [62.5, 117.3] 0.257
 B cell (count/μL) 171.0 [132.5, 265.0] 248.0 [146.0, 328.5] 0.493 68.5 [58.5, 126.8] 115.0 [94.3, 156.0] 0.299