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Table 1 Baseline characteristics, clinical care and outcomes, and indirect calorimetry measured resting energy expenditure in COVID-19 ICU patients

From: Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19

(a) Baseline characteristics (n = 22)
 Age (mean, range) 58 (31–88)
 Male sex (n, %) 13 (59)
 Race (n, %)
  African-American/Black 12 (54)
  Caucasian/White 7 (32)
  Hispanic 3 (14)
 BMI (mean, range) 30.7 (17.4–48.1)
 BMI > 30 (%) 55
 Ventilator days (21-day study period only) (mean, sd) 14.4 (4.7)
 Mortality (21-day study period only) (n, %) 3 (14)
 Mortality (hospital mortality) (n, %) 5 (22)
(b) Energy expenditure/data D0–7 D7–14 D14–21 p value
 Measured REE in absolute kCal/day (all patients) (median, IQR) 1568 (1175–2215) 1830 (1465–2467) 2789 (1776–3262) < 0.05
 Measured REE kCal/kg actual BW (non-obese, BMI < 30) (median, IQR) 19.2 (16.9–20.7) 26 (24.5–35.5) 29 (23–34.5) < 0.05
 Measured REE kCal/kg actual BW (obese, BMI > 30) (median, IQR) 17.5 (12–19.25) 21 (20–23.5) 31.5 (24.8–36) < 0.05
 Measured REE kCal/kg adjusted BW (obese, BMI > 30) (median, IQR) 20 (17–22.5) 26.3 (24–29) 32.5 (28.8–35.8) < 0.05
 Measured REE kCal/kg actual BW (all patients) (median, IQR) 19 (13.7–28.5) 26 (22–42) 30.4 (27–35.8) < 0.05
(c) Clinical data D0–7 D7–14 D14–21 p value
Use of prone positioning (%) (mean, sd) 12.3 (8.6) 7 (2.4) 12.2 (4.3) 0.17
Use of paralysis with neuromuscular blocker (%) (mean, sd) 14.8 (8) 9.7 (1.7) 12.3 (3.4) 0.2
SOFA score (mean, sd) 9 (3.6) 9 (3.2) 9.5 (3.6) 0.5
  1. a, patient characteristics; b, nutritional data for the first 3 weeks post-intubation; c, clinical care and outcomes data
  2. BW body weight; BMI body mass index; REE resting energy expenditure, predicted REE via Harris-Benedict equation; AdjBW adjusted bodyweight, ABW actual body weight, obesity BMI > 30, non-obese BMI < 30I, IQR interquartile range, SOFA Sequential Organ Failure Assessment, sd standard deviation
  3. Notes: All obese subjects had BMI measures between 30 and 50. p values are for Kruskal-Wallis test
  4. Subjects were withdrawn from this analysis upon extubation or death