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Table 1 Baseline characteristics of different cohorts

From: Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors

 

Persistent impairment

NA

Complete recovery

NA

Unclustered

NA

 

n

76

 

61

 

22

  

Age (years)

65 (54.3–72)

 

56 (43–70)

 

63 (52–69.3)

 

p = 0.002*

Male sex (n)#

47 (61.8%)

 

44 (72.1%)

 

16 (72.7%)

 

p = 0.205

ICULOS

23.0 (12.8–39.5)

2

19 (10.0–31.0)

6

40.5 (15.3–48.3)

2

p = 0.207

MV(day)

9 (2–20)

1

6 (2–22)

2

10 (4–29)

3

p = 0.746

CCI

3 (1–5.8)

 

3 (1–5)

1

2.5 (1.8–6)

 

p = 0.246

RRT (day)

0 (0–0.75)

 

0 (0–2.5)

3

0 (0–2.5)

 

p = 0.650

Tracheostomy (n)#

20 (26.3%)

21

18 (29.5%)

13

11 (50%)

3

p = 0.678

Intervention group (n)#

38 (50%)

 

38 (62.2%)

 

11(50%)

 

p = 0.150

Educationǂ$

5 (1–9)

 

5 (2–9)

 

5 (2–9)

 

p = 0.039*

BMI

27.8 (24.4–32.5)

 

25.8 (22.6–29.1)

1

26.7 (23–30)

2

p = 0.006*

Family statusǂ$

2 (1–6)

1

2(1–6)

 

2(1–4)

1

p = 0.021*

No. of ICD diagnoses at discharge

9 (6–15)

 

9 (5–11)

 

8 (6–15.8)

 

p = 0.077

  1. Data are shown as medians (interquartile ranges), except for percentages and mode (range). p values represent Mann-Whitney U tests between persistent impairment and complete recovery, except for #chi-squared test
  2. ICULOS intensive care length of stay (days), MV(d) period of mechanical ventilation (days), CCI Charlston Co-morbidity Index, RRT(d) renal replacement therapy (days) and NA not available
  3. $Indicated mode (range) with the significance taken to be p < 0.05
  4. *p < 0.05
  5. Ç‚Categories shown in Additional Table 1