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Table 1 Clinical characteristics and baseline laboratory findings of patients infected with SARS-CoV-2

From: Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China

 

All patients (n = 317)

Moderate patients (n = 93)

Severe patients (n = 167)

Critical patients (n = 57)

Characteristics

 Age, years

62.0 (51.0–70.0)

59.0 (46.0–68.5)

62.0 (51.0–69.0)*

68.0 (57.0–77.0)*

 Males, n (%)

162 (51.1%)

41 (44.1%)

90 (53.9%)

31 (54.4%)

 Comorbidity

  Chronic respiratory diseases, n (%)

19 (6.0%)

4 (4.3%)

9 (5.9%)

6 (10.5%)

  Hypertension, n (%)

124 (39.1%)

40 (43.0%)

61 (36.5%)

23 (40.4%)

  Coronary artery disease, n (%)

30 (9.5%)

10 (10.8%)

14 (8.4%)

6 (10.5%)

  Diabetes mellitus, n (%)

63 (19.9%)

17 (18.3%)

30 (18.0%)

16 (28.1%)

  Chronic kidney disease, n (%)

4 (1.3%)

3 (3.2%)

1 (0.6%)

0

  Tumor, n (%)

6 (1.9%)

3 (3.2%)

2 (1.2%)

1 (1.8%)

Laboratory findings

 White blood cell count, × 10^9/L

5.6 (4.4–7.8)

5.4 (4.2–6.7)

5.2 (4.2–7.2)

8.6 (5.9–13.4)*#

 Neutrophil count, × 10^9/L

4.0 (2.9–6.3)

3.5 (2.6–4.3)

3.9 (2.8–5.4)

7.5 (4.7–12.4)*#

 Lymphocyte count, × 10^9/L

0.9 (0.6–1.3)

1.0 (0.8–1.5)

0.9 (0.7–1.2)

0.6 (0.5–0.8)*

 Hemoglobin, g/L

127.0 (116.0–139.0)

125.0 (114.5–134.0)

127.0 (116.0–139.0)

133.0 (117.5–140.5)

 Platelet count, × 10^9/L

208.0 (154.0–285.0)

223.0 (173.0–307.5)

201.0 (151.0–276.0)

181.0 (124.0–257.0)*

 Albumin, g/L

33.7 (30.8–36.8)

36.4 (32.9–40.0)

33.5 (31.2–36.2)*

30.7 (28.2–33.4)*#

 Blood bicarbonate ions, mmol/L

23.5 (21.7–25.1)

23.9 (21.9–25.6)

23.6 (22.0–25.0)

22.2 (19.3–24.3)*#

 Blood urea nitrogen, mmol/L

4.6 (3.5–6.0)

4.0 (3.3–5.0)

4.4 (3.5–5.5)

7.2 (5.1–10.7)*#

 Blood creatinine, μmol/L

70.0 (57.5–86.0)

62.0 (55.0–81.5)

69.0 (59.0–84.0)

79.0 (62.0–103.5)*#

 Lactate dehydrogenase, U/L

302.0 (237.0–425.0)

234.0 (209.0–283.5)

307.0 (249.0–392.0)*

496.0 (415.0–690.0)*#

 High-sensitivity C-reactive protein, mg/L

41.1 (11.8–90.6)

14.0 (4.8–39.7)

44.1 (15.4–89.0)*

93.0 (65.0–165.1)*#

 Procalcitonin, ng/mL

0.06 (0.03–0.17)

0.04 (0.02–0.07)

0.06 (0.03–0.14)*

0.21 (0.10–0.70)*#

 Ferritin, μg/L

751.5 (435.7–1333.9)

504.0 (282.0–776.4)

784.0 (456.1–1325.6)*

1340.0 (884.6–1989.4)*#

 Soluble interleukin-2 receptor, U/mL

762.0 (509.9–1124.0)

655.0 (483.5–916.5)

762.0 (576.0–1060.0)*

1174.0 (915.0–1552.5)*#

 Interleukin-6, pg/mL

21.7 (7.3–53.9)

13.1 (3.8–23.5)

21.7 (6.3–53.9)*

59.7 (33.5–137.4)*#

 Interleukin-8, pg/mL

15.5 (9.4–26.6)

12.2 (7.8–9.0)

15.5 (9.7–26.1)*

26.0 (14.9–49.4)*#

 Interleukin-10, pg/mL

5.6 (5.00–9.4)

5.0 (5.0–6.8)

5.3 (5.0–8.8)

9.5 (6.7–15.9)*#

 Tumor necrosis factor alpha, pg/mL

9.1 (7.2–12.1)

8.7 (6.8–10.8)

9.0 (7.1–11.6)*

11.0 (8.0–14.8)*#

 hsCRP/lymphocyte, × 10^-9 mg

53.5 (10.5–128.1)

10.8 (3.4–49.6)

56.0 (15.8–115.4)*

142.1 (82.3–300.4)*#

  1. Data are expressed as median (IQR) or n (%). *P < 0.05 represents significant differences between severe or critically ill group and moderate group, #P < 0.05 represents significant differences between critically ill group versus severe group