Table 1 Demographics and baseline characteristics of enrolled patients
From: Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies
|  | COVID-19 cohort, n = 30 | Non-COVID-19 cohort, n = 30 |
|---|---|---|
Age, years | 70 [63–77] | 61 [51–69] |
Female sex, no. (%) | 7 (23) | 4 (13) |
Height, cm | 170 [170–175] | 171 [167–180] |
Predicted body weight, kg | 66 [62–75] | 66 [59–75] |
Body mass index, kg/m2 | 28 [25–29] | 33 [27–40] |
SOFA at study inclusion | 8 [7–10] | 14 [10–15] |
SAPS II | 45 [34–58] |  |
Comorbidities, no. (%) | ||
 Hypertension | 19 (63) |  |
 Active cancer | 3 (10) |  |
 Chronic obstructive pulmonary disease | 3 (10) |  |
 Diabetes mellitus | 2 (7) |  |
 Coronary artery disease | 1 (3) |  |
 Other | 10 (33) |  |
ARDS risk factors, no. (%) | ||
 Pneumonia | 30 (100) | 10 (33) |
 Aspiration | 0 (0) | 4 (13) |
 Extrapulmonary sepsis | 0 (0) | 4 (13) |
 Trauma | 0 (0) | 2 (7) |
 Other | 0 (0) | 10 (33) |
Noninvasive respiratory support before intubation, no. (%) | 20 (67) | Â |
Duration of noninvasive respiratory support before intubation, hours | 19 [9–63] |  |
ARDS severity at enrollment, no. (%) | ||
 Moderate (PaO2/FiO2 ratio 101–200 mmHg) | 23 (77) | 22 (73) |
 Severe (PaO2/FiO2 ratio ≤ 100 mmHg) | 7 (23) | 8 (27) |
Prone positioning during the ICU stay, no. (%) | 21 (70) | Â |
Acute kidney failure, no. (%) | 15 (50) | Â |
ICU-acquired infection, no. (%) | 9 (30) | Â |
Pneumothorax, no. (%) | 4 (13) | Â |
Tracheostomy, no. (%) | 8 (27) | Â |
28-day outcome, no. (%) | ||
 Dead | 19 (63) | 9 (30) |
 Alive, receiving mechanical ventilation | 3 (10) |  |
 Alive, breathing unassisted | 8 (27) |  |