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Table 1 Demographics and baseline characteristics of enrolled patients

From: Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies

  COVID-19 cohort, n = 30 Non-COVID-19 cohort, n = 30
Age, years 70 [63–77] 61 [51–69]
Female sex, no. (%) 7 (23) 4 (13)
Height, cm 170 [170–175] 171 [167–180]
Predicted body weight, kg 66 [62–75] 66 [59–75]
Body mass index, kg/m2 28 [25–29] 33 [27–40]
SOFA at study inclusion 8 [7–10] 14 [10–15]
SAPS II 45 [34–58]  
Comorbidities, no. (%)
 Hypertension 19 (63)  
 Active cancer 3 (10)  
 Chronic obstructive pulmonary disease 3 (10)  
 Diabetes mellitus 2 (7)  
 Coronary artery disease 1 (3)  
 Other 10 (33)  
ARDS risk factors, no. (%)
 Pneumonia 30 (100) 10 (33)
 Aspiration 0 (0) 4 (13)
 Extrapulmonary sepsis 0 (0) 4 (13)
 Trauma 0 (0) 2 (7)
 Other 0 (0) 10 (33)
Noninvasive respiratory support before intubation, no. (%) 20 (67)  
Duration of noninvasive respiratory support before intubation, hours 19 [9–63]  
ARDS severity at enrollment, no. (%)
 Moderate (PaO2/FiO2 ratio 101–200 mmHg) 23 (77) 22 (73)
 Severe (PaO2/FiO2 ratio ≤ 100 mmHg) 7 (23) 8 (27)
Prone positioning during the ICU stay, no. (%) 21 (70)  
Acute kidney failure, no. (%) 15 (50)  
ICU-acquired infection, no. (%) 9 (30)  
Pneumothorax, no. (%) 4 (13)  
Tracheostomy, no. (%) 8 (27)  
28-day outcome, no. (%)
 Dead 19 (63) 9 (30)
 Alive, receiving mechanical ventilation 3 (10)  
 Alive, breathing unassisted 8 (27)  
  1. Data expressed in median [interquartile range], if not otherwise specified