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Table 1 Ventilator settings and measurements of in vivo individualized shared ventilation

From: Successful ventilation of two animals with a single ventilator: individualized shared ventilator setup in an in vivo model

  Individual ventilation Shared ventilator
Animal 1 Animal 2 Animal 1 Animal 2
Ventilator settings
 Tidal volume (ml) 600 800 1400
 PEEP (cmH2O) 3 4 3 7
 FiO2 0.3 0.3 1.0
 I/E ratio 1:2 1:2 1:1.5
 Respiratory rate (min−1) 20 20 20
Measured ventilatory values
 PEEP (cmH2O) 3 5 4 7
 Ppeak vent (cmH2O) 18 32 31
 Ppeak circuit (cmH2O)    19 18
 etCO2 31 33 32 29
Blood gas values
 pH 7.54 7.54 7.47 7.49
 PaO2 (mmHg) 112 230 443 376
 PaCO2 (mmHg) 31 30 39 36
Hemodynamic values
 BP (mmHg) 76/43 83/38 73/40 84/36
  1. Table 1 shows the settings of the ventilator per animal and for the shared ventilator in a volume-controlled ventilation. In animal 2, inline PEEP was applied; in animal 1, the flow restriction with our valve was applied to distribute the pressures as desired among the two animals.