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Table 1 Baseline characteristics of the study population

From: RNA-expression of adrenomedullin is increased in patients with severe COVID-19

 

COVID-19

Controls

 

n

21

19

 

Sex male

57.1%

57.9%

p = n.s.*

Agea

50 ± 16

56 ± 20

p = n.s.#

ICU admission

28.6%

5.3%

p = n.s.*

Death

19.0%

5.3%

p = n.s.*

Coronary artery disease

4.8%

36.8%

p = 0.02*

Chronic heart failure

4.8%

15.8%

p = n.s.*

Chronic obstructive pulmonary disease

0.0%

21.1%

p = 0.04*

Hypertension

28.6%

47.4%

p = n.s.*

Hyperlipidemia

9.5%

36.8%

p = n.s.*

Diabetes

4.8%

26.3%

p = n.s.*

Chronic renal failure

9.5%

21.1%

p = n.s.*

Heart frequency [bpm]a

96 ± 15

92 ± 27

p = n.s.#

Systolic blood pressure [mmHg]a

132 ± 20

134 ± 28

p = n.s.#

Oxygen saturationa

95 ± 4%

95 ± 3%

p = n.s.#

Respiratory rate [per minute]a

22 ± 7

21 ± 7

p = n.s.#

Temperature [°C]a

37.7 ± 0.7

37.4 ± 0.9

p = n.s.#

BMIa

27.8 ± 5.6

27.6 ± 5.3

p = n.s.#

NEWS-2 Scoreb

4 ± 5

3 ± 4

p = n.s.#

Creatinine [mg/dl]b

0.88 ± 0.58

0.95 ± 0.55

p = n.s.#

CRP [mg/l]b

43.4 ± 66.7

48.4 ± 74.0

p = n.s.#

WBC [/nl]b

7.2 ± 4.7

8.1 ± 7.9

p = n.s.#

IL-6 [pg/ml]b

30.7 ± 50.1

35.8 ± 87.5

p = n.s.#

ADM/GAPDH expressiona

0.88 ± 0.45

0.58 ± 0.35

p = 0.025

  1. *Tested with Fisher’s exact test
  2. #Tested with Mann-Whitney U test
  3. aValues are mean ± standard deviation
  4. bValues are median ± interquartile range