From: RNA-expression of adrenomedullin is increased in patients with severe COVID-19
 | COVID-19 | Controls |  |
---|---|---|---|
n | 21 | 19 | Â |
Sex male | 57.1% | 57.9% | p = n.s.* |
Agea | 50 ± 16 | 56 ± 20 | p = n.s.# |
ICU admission | 28.6% | 5.3% | p = n.s.* |
Death | 19.0% | 5.3% | p = n.s.* |
Coronary artery disease | 4.8% | 36.8% | p = 0.02* |
Chronic heart failure | 4.8% | 15.8% | p = n.s.* |
Chronic obstructive pulmonary disease | 0.0% | 21.1% | p = 0.04* |
Hypertension | 28.6% | 47.4% | p = n.s.* |
Hyperlipidemia | 9.5% | 36.8% | p = n.s.* |
Diabetes | 4.8% | 26.3% | p = n.s.* |
Chronic renal failure | 9.5% | 21.1% | p = n.s.* |
Heart frequency [bpm]a | 96 ± 15 | 92 ± 27 | p = n.s.# |
Systolic blood pressure [mmHg]a | 132 ± 20 | 134 ± 28 | p = n.s.# |
Oxygen saturationa | 95 ± 4% | 95 ± 3% | p = n.s.# |
Respiratory rate [per minute]a | 22 ± 7 | 21 ± 7 | p = n.s.# |
Temperature [°C]a | 37.7 ± 0.7 | 37.4 ± 0.9 | p = n.s.# |
BMIa | 27.8 ± 5.6 | 27.6 ± 5.3 | p = n.s.# |
NEWS-2 Scoreb | 4 ± 5 | 3 ± 4 | p = n.s.# |
Creatinine [mg/dl]b | 0.88 ± 0.58 | 0.95 ± 0.55 | p = n.s.# |
CRP [mg/l]b | 43.4 ± 66.7 | 48.4 ± 74.0 | p = n.s.# |
WBC [/nl]b | 7.2 ± 4.7 | 8.1 ± 7.9 | p = n.s.# |
IL-6 [pg/ml]b | 30.7 ± 50.1 | 35.8 ± 87.5 | p = n.s.# |
ADM/GAPDH expressiona | 0.88 ± 0.45 | 0.58 ± 0.35 | p = 0.025 |