Skip to main content

Table 1 Comparison between survivors and non-survivors

From: Substrate utilization and energy expenditure pattern in sepsis by indirect calorimetry

 

Survivors (n = 20)

Non-survivors (n = 14)

Demographics

 Age, median (IQR) (years)

63.5 (24–72.5)

63.5 (24–74)

 Male (%)

12 (60%)

12 (85.7%)

 BMI, median (IQR) Kg/m2

22.23 (15.4–22.8)

22.74 (18.61–22.07)

Clinical severity

 APACHE II, mean (SD)

27.5 ± 6.1

27.9 ± 9.3

 SOFA, mean (SD)

13.8 ± 2.8

15.1 ± 2.5

 mNUTRIC, mean (SD)

6.25 ± 1.61

6.21 ± 1.25

 SGA, median (IQR)

6 (3–6)

5 (1–5)

 Vasopressor use (%)

12 (60%)

11 (78.6%)

 Time to initiate feeding, median (range), hours

8.16 (3–45.1)

6.62 (3–23.25)

Comorbidities

 Diabetes mellitus (%)

10 (50%)

4 (28.6%)

 Ischemic heart disease (%)

5 (25%)

4 (28.6%)

 Cerebrovascular accident (%)

5 (25%)

1 (7.1%)

 Chronic liver disease (%)

3 (15%)

1 (7.1%)

 Chronic kidney disease (%)

7 (35%)

3 (21.4%)

 Malignancy (%)

2 (10%)

3 (21.4%)

 Connective tissue disease (%)

5 (25%)

4 (28.6%)

Diagnosis

 Pneumonia

8 (40%)

8 (57.1%)

 Line sepsis

2 (10%)

1 (7.1%)

 Other sites of sepsis

10 (50%)

5 (35.7%)

Details of calories and macronutrient delivered

 

Total

Day 1

Day 2

Day 3

Day 4

Day 5

Total

Day 1

Day 2

Day 3

Day 4

Day 5

Calories delivered, median, IQR (kcal)

4655.45 (3439.96–5716.79)

821.01 (384.25–999.65)

845.40 (669.03–1102.08)

1072.22 (815.25–1329.05)

953.37 (817.38–1281.80)

1139.75 (1028.50–1421.00)

4600.76 (3754.91–6067.63)

590.71 (330.82–896.00)

1038.65 (637.48–1584.00)

1143.54 (808.75–1620.66)

941.25 (753.12–1419.75)

1063.03 (76.25–1490.29)

Carbohydrates delivered, median, IQR (g)

498.50 (379.50–646.00)

51.58 (34.07–98.77)

106.87 (69.52–117.94)

117.93 (96.86–145.8)

117 (109.33–129.6)

126.22 (98.28–159.69)

482.00 (400.00–581.00)

35.21 (24.95–83.02)

101.83 (62.24–129.6)

103.53 (86.65–131.53)

107.56 (86.4–125.95)

107.56 (93.79–132.53)

Lipid delivered, median, IQR (g)

190.50 (158.00–294.00)

23.43 (10.59–52.17)

55.61 (19.02–69.36)

43.2 (34.38–69.33)

43.2 (31.20–67.00)

57.29* (47.52–69.33)

154.50 (109.00–282.00)

19.38 (7.60–28.62)

36.47 (26.13–51.84)

35.91 (23.10–53.72)

34.62 (24.66–71.02)

29.95* (25.01–55.95)

Protein delivered, median, IQR (g)

323.74 (261.78–372.05)

44.92 (25.49–66.47)

61.17 (47.01–79.98)

74.88 (55.2–86.84)

66.36 (30.33–77.80)

70.25 (62.59–91.15)

279.33 (110.16–398.17)

34.32 (34.32–17.41)

69 (30.78–76.48)

66.8 (47.66–86.14)

61.91 (42.80–90.78)

77.68 (43.22–88.32)

  1. Abbreviations: IQR interquartile range, BMI body mass index, APACHE Acute Physiology And Chronic Health Evaluation, SOFA sequential organ failure assessment, mNUTRIC modified Nutrition Risk in Critically ill, SGA Subjective Global Assessment, IC indirect calorimetry
  2. *p = 0.02