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Table 1 Comparison between survivors and non-survivors

From: Substrate utilization and energy expenditure pattern in sepsis by indirect calorimetry

  Survivors (n = 20) Non-survivors (n = 14)
Demographics
 Age, median (IQR) (years) 63.5 (24–72.5) 63.5 (24–74)
 Male (%) 12 (60%) 12 (85.7%)
 BMI, median (IQR) Kg/m2 22.23 (15.4–22.8) 22.74 (18.61–22.07)
Clinical severity
 APACHE II, mean (SD) 27.5 ± 6.1 27.9 ± 9.3
 SOFA, mean (SD) 13.8 ± 2.8 15.1 ± 2.5
 mNUTRIC, mean (SD) 6.25 ± 1.61 6.21 ± 1.25
 SGA, median (IQR) 6 (3–6) 5 (1–5)
 Vasopressor use (%) 12 (60%) 11 (78.6%)
 Time to initiate feeding, median (range), hours 8.16 (3–45.1) 6.62 (3–23.25)
Comorbidities
 Diabetes mellitus (%) 10 (50%) 4 (28.6%)
 Ischemic heart disease (%) 5 (25%) 4 (28.6%)
 Cerebrovascular accident (%) 5 (25%) 1 (7.1%)
 Chronic liver disease (%) 3 (15%) 1 (7.1%)
 Chronic kidney disease (%) 7 (35%) 3 (21.4%)
 Malignancy (%) 2 (10%) 3 (21.4%)
 Connective tissue disease (%) 5 (25%) 4 (28.6%)
Diagnosis
 Pneumonia 8 (40%) 8 (57.1%)
 Line sepsis 2 (10%) 1 (7.1%)
 Other sites of sepsis 10 (50%) 5 (35.7%)
Details of calories and macronutrient delivered
  Total Day 1 Day 2 Day 3 Day 4 Day 5 Total Day 1 Day 2 Day 3 Day 4 Day 5
Calories delivered, median, IQR (kcal) 4655.45 (3439.96–5716.79) 821.01 (384.25–999.65) 845.40 (669.03–1102.08) 1072.22 (815.25–1329.05) 953.37 (817.38–1281.80) 1139.75 (1028.50–1421.00) 4600.76 (3754.91–6067.63) 590.71 (330.82–896.00) 1038.65 (637.48–1584.00) 1143.54 (808.75–1620.66) 941.25 (753.12–1419.75) 1063.03 (76.25–1490.29)
Carbohydrates delivered, median, IQR (g) 498.50 (379.50–646.00) 51.58 (34.07–98.77) 106.87 (69.52–117.94) 117.93 (96.86–145.8) 117 (109.33–129.6) 126.22 (98.28–159.69) 482.00 (400.00–581.00) 35.21 (24.95–83.02) 101.83 (62.24–129.6) 103.53 (86.65–131.53) 107.56 (86.4–125.95) 107.56 (93.79–132.53)
Lipid delivered, median, IQR (g) 190.50 (158.00–294.00) 23.43 (10.59–52.17) 55.61 (19.02–69.36) 43.2 (34.38–69.33) 43.2 (31.20–67.00) 57.29* (47.52–69.33) 154.50 (109.00–282.00) 19.38 (7.60–28.62) 36.47 (26.13–51.84) 35.91 (23.10–53.72) 34.62 (24.66–71.02) 29.95* (25.01–55.95)
Protein delivered, median, IQR (g) 323.74 (261.78–372.05) 44.92 (25.49–66.47) 61.17 (47.01–79.98) 74.88 (55.2–86.84) 66.36 (30.33–77.80) 70.25 (62.59–91.15) 279.33 (110.16–398.17) 34.32 (34.32–17.41) 69 (30.78–76.48) 66.8 (47.66–86.14) 61.91 (42.80–90.78) 77.68 (43.22–88.32)
  1. Abbreviations: IQR interquartile range, BMI body mass index, APACHE Acute Physiology And Chronic Health Evaluation, SOFA sequential organ failure assessment, mNUTRIC modified Nutrition Risk in Critically ill, SGA Subjective Global Assessment, IC indirect calorimetry
  2. *p = 0.02