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Table 1 Use of respiratory interventions in COVID-19 patient population

From: Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19

Study Huang et al. [5]
(n = 41)
Wu et al. [6] (n = 201) Wang et al. [7]
(n = 138)
Guan et al. [8]
(n = 1099)
Yang et al. [9]
(n = 52)
Arentz et al. [10]
(n = 21)
Grasseli et al. [11]
(n = 1591)
Richardson et al. [12]
(n = 5700)
Study design Prospective cohort, single center Retrospective cohort, single center Retrospective, single-center case series Retrospective data from 552 hospitals in China Retrospective cohort, single center Retrospective cohort, single center Retrospective case series Retrospective case series
Study population Confirmed COVID-19 cases from Dec 16, 2019, to Jan 2, 2020 Confirmed COVID-19 cases from Dec 25, 2019, to Jan 26, 2020 Confirmed COVID-19 cases from Jan 1 to Jan 28, 2020 Confirmed COVID-19 cases through January 29, 2020 Critically illb confirmed COVID-19 cases from late Dec 2019 to Jan 26, 2020 Confirmed COVID-19 cases admitted to ICU from Feb 20 to March 5, 2020 Critically ill laboratory-confirmed COVID-19 cases from Feb 20 to March 18, 2020 Confirmed COVID-19 cases admitted to 12 hospitals in New York City from March 1 to April 4, 2020
Age 49 (IQR, 41–58) 51 (IQR, 43–60) 56 (IQR, 42–68) 47 (IQR 35–58) 59.7 (± 13.3) 70 (IQR, 43–92) 63 (IQR, 56–70) 63 (IQR, 52–75)
ICU admission 13 (32%) 53 (26.4%) 36 (26%) 55 (5%) 52 (100%) 21 (100%) 1591 (100%) 373/2634 (14.2%)
Acute respiratory distress syndrome 12 (29%) 84 (41.8%) 27 (19.6%) 37 (3.4%) 35 (67%) 20 (95%) NR NR
Oxygen therapy 27 (66%) 98 (49%) 106 (77%) 454 (41.3%) NR NR 13/1300 (1%) 1584/5693 (27.8%)
High-flow nasal cannula 10 (24%)a NR NR NR 33 (63.5%) 1 (4.8%) NR NR
Non-invasive ventilation 10 (24%)a 61 (30%) 15 (10.9%) 56 (5.1%) 29 (56%) 4 (19%) 137/1300 (11%) NR
Invasive mechanical ventilation 2 (5%) 5 (2.5%) 17 (12.3%) 25 (2.3%) 22 (42%) 15 (71%) 1150/1300 (88%) 320/2634 (12.2%)
Prone position ventilation NR NR NR NR 6 (11.5%) 8 (38%) 240/875 (27%) NR
ECMO 2 (5%) 1 (0.5%) 4 (2.9%) 5 (0.5%) 6 (11.5%) NR 5/498 (1%) NR
  1. Abbreviations: ICU intensive care unit, IMV invasive mechanical ventilation, ECMO extracorporeal membrane oxygenation, NR not reported
  2. aReported as NIV or HFNC use; bdefined as those admitted to ICU requiring mechanical ventilation or had FiO2 ≥ 0.6