TY - JOUR AU - Miller, Joseph AU - Bruen, Charles AU - Schnaus, Michael AU - Zhang, Jeffrey AU - Ali, Sadia AU - Lind, April AU - Stoecker, Zachary AU - Stauderman, Kenneth AU - Hebbar, Sudarshan PY - 2020 DA - 2020/08/14 TI - Auxora versus standard of care for the treatment of severe or critical COVID-19 pneumonia: results from a randomized controlled trial JO - Critical Care SP - 502 VL - 24 IS - 1 AB - Calcium release-activated calcium (CRAC) channel inhibitors stabilize the pulmonary endothelium and block proinflammatory cytokine release, potentially mitigating respiratory complications observed in patients with COVID-19. This study aimed to investigate the safety and efficacy of Auxora, a novel, intravenously administered CRAC channel inhibitor, in adults with severe or critical COVID-19 pneumonia. SN - 1364-8535 UR - https://doi.org/10.1186/s13054-020-03220-x DO - 10.1186/s13054-020-03220-x ID - Miller2020 ER -