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Table 3 Vital signs and arterial blood gas analysis

From: High-flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease patients after extubation: a multicenter, randomized controlled trial

 

HR (bpm)

MAP (mmHg)

RR (bpm)

pH

PaCO2 (mmHg)

PaO2/FiO2 (mmHg)

NIV (n = 42)

 Baseline

87.5 (80.8–101.5)

84.5 ± 10.3

21 (16–26)

7.45 (7.40–7.49)

53 (48.8–61.3)

229.3 ± 42.0

 1 h

90.5 (80–108.3)

86.8 ± 10.2

25.5 (18–28)*

7.44 (7.39–7.48)

55 (48.8–61.3)

218.9 ± 37.8*

 24 h

94 (79.8–105.3)

87.6 ± 11.1

24.5 (18–27)*

7.45 (7.41–7.48)

52.5 (49–57.3)

222.4 ± 34.5

 48 h

93.5 (79.5–107.5)

87.7 ± 12.6

21.5 (16.8–26)

7.45 (7.41–7.48)

52 (49–56)

227.2 ± 40.5

 p valuea

0.083

0.097

0.000

0.884

0.542

0.002

HFNC (n = 44)

 Baseline

92 (80.5–107.8)

88 ± 6.0

18 (16–23)

7.48 (7.42–7.51)

50.5 (48–57.8)

239.2 ± 47.0

 1 h

94.5 (86–103.8)

89.7 ± 7.9

21 (18–25)*

7.42 (7.40–7.48)*

56 (49.3–59)*

220.5 ± 36.3*

 24 h

93 (80.3–99.8)

87.0 ± 8.8

20 (17.3–24.5)#

7.44 (7.41–7.48)

54 (49–58)

228.4 ± 35.3

 48 h

92 (82.3–103.3)

86.1 ± 8.1

19 (16.3–23.8)

7.43 (7.41–7.49)

51 (49–57.8)

230.3 ± 36.0

 p valuea

0.454

0.129

0.009

0.002

0.016

0.000

  1. Data are shown as means ± standard deviation or median (interquartile range)
  2. HFNC high-flow nasal cannula oxygen therapy, NIV non-invasive ventilation, HR heart rate, MAP mean arterial pressure, RR respiratory rate, PaCO2 partial pressure of arterial carbon dioxide, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspiration oxygen
  3. *Compared with the baseline value in the same group, p < 0.05 after Bonferroni correction
  4. #Compared with NIV at the same time point, p < 0.05
  5. aComparison of multiple time points within the group