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Table 4 ECCO2R treatment initiation criteria for patients with ae-COPD

From: ECCO2R therapy in the ICU: consensus of a European round table meeting

Initiation criteria for patients at risk of NIV failure

Parameter

  No decrease in PaCO2 while on NIV

Consensus

  No decrease in respiratory rate while on NIV

Consensus

  Clinical signs of respiratory failure

Majority agreement

  pH 7.25–7.30

Majority agreement

  Baseline PaCO2

No agreement

  Baseline respiratory rate

No agreement

Initiation criteria for patients who are already intubated

 - Patients who look like they will not be extubated early without ECCO2R

   Previous intubation for ae-COPD

   Has failed a spontaneous breathing trial due to increased dyspnoea

   Reintubation after first extubation attempt despite NIV

   Patients with severe bronchospasm who are difficult/impossible to ventilate adequately or otherwise not responding to medical treatment

   Patients who remain hypercapnic and not improving with MV

 - No hypoxemia preventing extubation

 - MV < 72 h

 - Patients with home NIV and good quality of life

  1. Criteria for ECCO2R treatment considered to be of importance and selected from the provided list. Target describes any potential target values identified. Consensus means a consensus threshold (≥ 80%) was reached, majority agreement means ≥ 50% agreed but consensus level was not reached, and no agreement means < 50% agreed
  2. Scoring and ranking was not conducted for this section during the meeting