Table 1 Patient characteristics
Characteristic | DEX group (n = 100) | Non-DEX group (n = 101) | P value |
|---|---|---|---|
Age (years), mean (SD) | 68 (14.9) | 69 (13.6) | 0.75 |
Men, n (%) | 63 (63) | 64 (63) | 0.96 |
Body weight (kg), mean (SD) | 55 (12.5) | 58 (15.3) | 0.09 |
COPD, n (%) | 8 (8) | 9 (9) | 0.82 |
Soft tissue infection, n (%) | 8 (8) | 10 (10) | 0.64 |
Emergency surgery, n (%) | 37 (37) | 36 (36) | 0.84 |
Site of infection, n (%) | |||
 Abdomen | 39 (39) | 35 (35) | 0.52 |
 Thorax | 39 (39) | 33 (33) | 0.35 |
 Urinary tract | 6 (6) | 10 (10) | 0.31 |
 Pancreatitis | 3 (3) | 9 (9) | 0.13 |
 Skin and soft tissue | 6 (6) | 7 (7) | 0.79 |
 Central nervous system | 1 (1) | 1 (1) | 1.00 |
 Others | 6 (6) | 6 (6) | 0.99 |
APACHE II score, median [IQR] | 23 [18, 29] | 22 [16, 29.5] | 0.51 |
SOFA score, median [IQR] | 8 [6, 11] | 9 [5, 11] | 0.67 |
SOFA respiratory score, median [IQR] | 2 [1, 3] | 2 [1, 3] | 0.86 |
SOFA circulatory score, median [IQR] | 3 [2, 4] | 3 [1.5, 4] | 0.44 |
SOFA renal score, median [IQR] | 1 [0, 2] | 1 [0, 3] | 0.28 |
SOFA hepatic score, median [IQR] | 0 [0, 1] | 0 [0, 1] | 0.42 |
SOFA neurological score, median [IQR] | 1 [0, 2] | 0 [0, 3] | 0.87 |
SOFA coagulation score, median [IQR] | 0 [0, 2] | 1 [0, 2] | 0.26 |
CRP (mg/dL), median [IQR] | 13.8 [6.0, 25.7] | 16.8 [6.4, 25.8] | 0.64 |
PCT (ng/mL), median [IQR] | 15.2 [2.8, 44.9] | 14.6 [1.5, 81.5] | 0.70 |
ALB (g/dL), mean (SD) | 2.6 (0.7) | 2.7 (0.7) | 0.64 |
PLT (109/L), median [IQR] | 170 [98, 227] | 141 [95, 224] | 0.34 |
PT (INR), median [IQR] | 1.21 [1.06, 1.37] | 1.24 [1.08, 1.45] | 0.34 |
FDPs (mcg/mL), median [IQR] | 16.0 [7.8, 29.3] | 17.4 [8.8, 33.5] | 0.80 |
SIRS criteria ≥ 3, n (%) | 71 (71) | 75 (74) | 0.60 |
DIC, n (%) | 40 (40) | 42 (42) | 0.87 |