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Fig. 2 | Critical Care

Fig. 2

From: A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection

Fig. 2

Regional volumetric strain maps in a 3-h murine model of patient self-inflicted lung injury randomized to two groups: Group I: subjects with induced lung injury on low tidal volume mechanical ventilation at the beginning of the experiment (T1) and at the end of the experiment (T3) (upper left and right panels). Group II: subjects with induced lung injury on spontaneous breathing (no mechanical ventilation) at the beginning of the experiment (T1) and at the end of the experiment (T3) (lower left and right panels). Progression of regional strain and heterogeneity in time is observed in spontaneous breathing, which reaches volumetric strain levels of up to 80%. Regional strain distribution remains more uniform and homogeneous in low tidal volume mechanical ventilation

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Critical Care

ISSN: 1364-8535