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Fig. 2 | Critical Care

Fig. 2

From: Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19

Fig. 2

Associations between sACE2 and biomarkers of metabolic syndrome, inflammation, and liver damage. a Marginal Effect size (B) estimates from robust linear regressions predicting sACE2 from biomarkers estimated for men and women separately. Biomarkers for which a significant interaction with sex was established are marked with an asterisk. b Partial Spearman correlations between study biomarkers and sACE2 levels. c Scatterplot of associations between GGT and sACE2. BMI, body mass index; MAP, mean arterial blood pressure; HbA1c, glycohemoglobin A1c; HOMA-IR, homeostatic model assessment of insulin resistance; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; IL-8, interleukin 8; hsCRP, high-sensitivity C-reactive protein; ALAT, alanine aminotransferase; ASAT, aspartate transaminase; GGT, gamma-glutamyl-transferase

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Critical Care

ISSN: 1364-8535