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Table 1 Characteristics of studies included in our systematic review

From: Neurological manifestations of COVID-19: a systematic review

SN Study Type of publication Country Source Neurological manifestation
1 Mao 2020 [5] Retrospective study China JAMA Neurology Total patients: 214
Any: 78 (36.44%)
CNS: 53 (24.76%)
• Dizziness: 36 (16.82%)
• Headache: 28 (13.08%)
• Impaired consciousness: 16 (7.4%)
• Acute cerebrovascular disease: 6 (2.8%)
• Ataxia: 1 (0.5%)
• Epilepsy: 1 (0.5%)
PNS: 19
• Hypoguesia: 12 (5.6%)
• Hyposmia: 11 (5.14%)
• Neuralgia: 5 (2.33%)
Muscle injury: 23 (10.74%)
2 Li 2020 [7] Retrospective study China SSRN (preprint) Total patients: 224
• Acute ischemic stroke: 11 (5%)
• Cerebral venous sinus thrombosis: 1 (0.5%)
• Intracerebral hemorrhage: 1 (0.5%)
3 Toscano 2020 [8] Case-report/series Italy The New England Journal of Medicine Guillain-Barré syndrome
4 Zhao Hua 2020 [9] Case-report/series China The Lancet Neurology Guillain-Barré syndrome
5 Gutiérrez-ortiz 2020 [10] Case-report/series Spain Neurology Miller Fisher syndrome and polyneuritis cranialis
6 Poyiadji 2020 [11] Case-report/series USA Radiology Encephalitis
7 Huaxia 2020 [12] Newspaper article China Xinhua News Encephalitis
8 Zhai 2020 [13] Case-report/series China Research square (preprint) Ischemic stroke
9 Sharifi-Razavi 2020 [14] Case-report/series Iran New Microbes and New Infections Intra-cerebral hemorrhage
10 Filatov 2020 [15] Case-report/series USA Cureus Encephalopathy
11 Zhao Kang 2020 [16] Case-report/series China medRxiv (preprint) Acute myelitis
12 Karimi 2020 [17] Case-report/series Iran Iran Red Crescent Medical Journal Encephalopathy
13 Chen Tao 2020 [18] Retrospective study China BMJ Total: 274 patients
• Myalgia: 60
• Headache: 31
• Hypoxic encephalopathy: 24
14 Qiu 2020 [19] Retrospective study China The Lancet Infectious disease Total: 36 patients
• Headache: 3 patients
15 Zhou 2020 [20] Retrospective study China The Lancet Total: 191 patients
• Myalgia: 29 patients
16 Guan 2020 [1] Retrospective study China The New England Journal of Medicine Total: 1099 patients
• Headache: 150 patients
• Myalgia: 164
17 Chen Nanshan 2020 [21] Retrospective study China The Lancet Total: 99 patients
• Headache: 8
• Myalgia: 11
• Confusion: 9
18 Huang 2020 [2] Retrospective study China The Lancet Total: 41
• Myalgia: 18
• Headache: 3
19 Wang 2020 [22] Retrospective study China JAMA Total: 138
• Myalgia: 48
• Headache: 9
20 Giacomelli 2020 [23] Retrospective study Italy Clinical Infectious Diseases Smell/taste disorder
21 Moriguchi 2020 [24] Case-report/series Japan International Journal of Infectious Diseases Meningitis/encephalitis
22 Jin 2020 [25] Case-report/series China Emerging Infectious Diseases Rhabdomyolysis
23 Fu 2020 [26] Case-report/series China Research square (preprint) Two cases of ischemic stroke
24 Ye 2020 [27] Case-report/series China Brain, Behavior, and Immunity Encephalitis
25 Wan 2020 [28] Case-report/series China Research Square (preprint) Bell’s palsy
26 Pilotto 2020 [29] Case-report/series Italy medRxiv (preprint) Encephalopathy
27. Zhang 2020 [30] Case-report/series USA medRxiv (preprint) Acute disseminated encephalomyelitis
28. Bernard-valnet 2020 [31] Case-report/series Switzerland medRxiv (preprint) Encephalitits
29. Padroni 2020 [32] Case-report/series Italy Journal of Neurology Guillain-Barré syndrome
30. Sedaghat 2020 [33] Case-report/series Iran Journal of Clinical Neuroscience Guillain-Barré syndrome
31. Virani 2020 [34] Case-report/series USA ID Cases Guillain-Barré syndrome
32. Yan 2020 [35] Retrospective study USA International Forum of Allergy & Rhinology Smell/taste disorder
33. Lechien 2020 [36] Prospective study Multicentre study in Europe European archives of oto-rhino-laryngology Smell/taste disorder
34. Moein 2020 [37] Prospective study Iran International Forum of Allergy & Rhinology Smell/taste disorder
35. Haddadi 2020 [38] Case-report/series Iran Cureus Intracerebral hemorrhage
36. Oxley 2020 [39] Case-report/series USA The New England Journal of Medicine Ischemic stroke
37. Lu 2020 [40] Retrospective study China Epilepsia Total patients: 304
• Encephalopathy: 8