Table 4 Virological findings on admission and on day 7
Total | Standard of care | Lopinavir/ritonavir | Hydroxy-chloroquine | p value | |
|---|---|---|---|---|---|
Respiratory RT-PCR at admission | |||||
Patients, n | 80 | 22 | 20 | 38 | – |
Samples analyzed, n (%) | 67 (84) | 21 (95) | 13 (65) | 33 (87) | – |
CT value | 25 (23–30) | 26 (24–31) | 25 (23–30) | 24 (21–29) | 0.498 |
Plasma RT-PCR at admission | |||||
Patients, n | 80 | 22 | 20 | 38 | – |
Samples analyzed, n (%) | 23 (29) | 5 (23) | 3 (15) | 15 (39) | – |
Negative RT-PCR, n (%) | 11 (48) | 4 (80) | 0 (0) | 7 (47) | 0.09 |
Positive RT-PCR, n (%) | 12 (52) | 1 (20) | 3 (15) | 8 (53) | |
CT value | 30 (29–33) | 35 (35–35) | 30 (29–31) | 30 (29–32) | NA* |
Respiratory RT-PCR at day 7 | |||||
Patients, n | 80 | 22 | 20 | 38 | – |
Samples analyzed, n (%) | 51 (64) | 14 (64) | 11 (55) | 26 (68) | – |
Negative RT-PCR, n (%) | 14 (27) | 2 (14) | 5 (45) | 7 (27) | 0.222 |
Positive RT-PCR, n (%) | 37 (73) | 12 (86) | 6 (55) | 19 (73) | |
CT value | 29 (27–34) | 28 (27–32) | 29 (25–29) | 32 (28–35) | 0.514 |
Plasma RT-PCR at day 7 | |||||
Patients, n | 80 | 22 | 20 | 38 | – |
Samples analyzed, n (%) | 54 (68) | 13 (59) | 13 (65) | 28 (74) | – |
Negative RT-PCR, n (%) | 42 (78) | 11 (85) | 9 (69) | 22 (79) | 0.634 |
Positive RT-PCR, n (%) | 12 (22) | 2 (15) | 4 (31) | 6 (21) | |
CT value | 32 (30–36) | 38 (38–38) | 31 (30–32) | 32 (29–34) | 0.237 |