12 | Hypotension | Blood pressure < 90 mmHg | 0.27 | 0.34 |
Bradycardia | Heart rate < 50 beats/min | 0.09 | 0. 10 | |
Hypotension and bradycardia | 0.33 | 0.38 | ||
25 | Bradycardia | None provided | 0.04 | 0.07 |
Acute coronary syndrome | None provided | 0.01 | 0.01 | |
30 | Hypotension | Requiring vasopressor support | 0 | 0 |
Bradycardia | Requiring interruption of study drug | 0 | 0.03 | |
Agitation | 0.04 | 0.03 | ||
34 | Hypoxemia | < 90% or decrease 5% Up to 24 h after surgery | 0. 11 | 0.07 |
Bradycardia | (< 55, or decrease > 20% if initial rate < 70 Up to 24 h after surgery | 0. 15 | 0. 17 | |
Tachycardia | > 160 or if initial rate > 113 then 20% Up to 24 h after surgery | 0. 10 | 0.07 | |
Hypotension | SBP < 95 of if SBP < 120 then 20% | 0.29 | 0.33 | |
Hypertension | SBP > 160 or if SBP > 133 then 20% Up to 24 h after surgery | 0. 14 | 0. 10 |