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Table 3 Higher cystatin C is associated with 60-day mortality in subjects with and without AKI

From: Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy

 

OR (95% CI)

p value

Full cohort (n = 919)

 Cystatin C Q4

1.8 (1.2–2.6)

0.003

With acute kidney injury (n = 486)

 Cystatin C Q4

1.6 (1.0–2.4)

0.048

Without acute kidney injury (n = 433)

 Cystatin C Q4

2.4 (1.2–5.0)

0.017

  1. All analyses compare the highest quartile to the lower three quartiles
  2. Q4—highest quartile of cystatin C with quartiles determined by ranges of cystatin C in full cohort
  3. All models adjusted for sepsis, age, sex, APACHE III, treatment arm, and LCA subphenotype. Full cohort model also adjusted for acute kidney injury (AKI) by Kidney Disease: Improving Global Outcomes (KDIGO) creatinine-based definition
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Critical Care

ISSN: 1364-8535