|
Outcomes
|
CVP
|
NO CVP
|
Effect size
|
p value
|
|---|
|
Primary outcome
|
|
28-day mortality
|
396/2174 (18.2)
|
500/2174 (23)
|
0.118
|
< 0.001
|
|
Secondary outcomes
|
|
In-hospital mortality
|
366/2174 (16.8)
|
415/2174 (19.1)
|
0.059
|
0.058
|
|
1-year mortality
|
789/2174 (36.3)
|
920/2174 (42.3)
|
0.124
|
< 0.001
|
|
AKI within 7 days, n (%)
|
1722/2174 (79.2)
|
1692/2174 (77.8)
|
0.029
|
0.355
|
|
Volume of IVF on day 1(mL)
|
2380 (1037–4245)
|
1897.5 (890–3070)
|
0.327
|
< 0.001
|
|
Volume of IVF on day 2 (mL)
|
997 (289.2–2150)
|
1000 (268.25–1953.6)
|
0.142
|
0.054
|
|
Volume of IVF on day 3 (mL)
|
605 (240–1500)
|
625 (230–1580.5)
|
0.051
|
0.942
|
|
Vasopressor-free day in 28 days
|
26.6 (25–27.4)
|
26.2 (22.9–27.2)
|
0.472
|
< 0.001
|
|
Ventilation-free day in 28 days
|
25.8 (22.3–27.1)
|
23.3 (17.3–26.2)
|
0.291
|
< 0.001
|
|
Delta-lactate
|
1.48 (2.35)
|
1.13 (2.32)
|
0.148
|
0.029
|
- IVF intravenous fluid, AKI acute kidney injury
