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Table 3 Sepsis and organ system dysfunction in the 72 h preceding death

From: Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study

 

All patients

ARDS present

ARDS absent

p

N = 385

N = 127

N = 258

Sepsis and severe organ system dysfunction—no. (%)

 Sepsis

273 (71%)

107 (84%)

166 (64%)

< 0.001

 Neurologic

151 (39%)

58 (46%)

93 (36%)

0.07

 Pulmonary

270 (70%)

104 (82%)

166 (64%)

< 0.001

 Cardiac

112 (29%)

31 (24%)

81 (31%)

0.16

 Hepatic

33 (9%)

11 (9%)

22 (9%)

0.96

 Gastrointestinal

19 (5%)

7 (6%)

12 (5%)

0.71

 Hemorrhage

54 (14%)

15 (12%)

39 (15%)

0.38

 Hematologic

120 (31%)

52 (41%)

68 (26%)

0.004

 Renal

122 (32%)

47 (37%)

75 (29%)

0.12

Septic shock and irreversible organ system dysfunction—no. (%)

 Septic shock

136 (35%)

57 (45%)

79 (31%)

0.006

 Neurologic

83 (22%)

22 (17%)

61 (24%)

0.16

 Pulmonary

19 (5%)

12 (9%)

7 (3%)

0.004

 Cardiac

95 (25%)

26 (20%)

69 (27%)

0.18

 Hepatic

23 (6%)

8 (6%)

15 (6%)

0.85

 Gastrointestinal

18 (5%)

6 (5%)

12 (5%)

0.97

 Hemorrhage

33 (9%)

11 (9%)

22 (9%)

0.96

 Hematologic

14 (4%)

4 (3%)

10 (4%)

0.72

 Renal

10 (3%)

3 (2%)

7 (3%)

0.84

Multi-organ failure—no. (%)

 Multi-organ failure

214 (56%)

76 (60%)

138 (53%)

0.24

 Sepsis + multi-organ failure

162 (42%)

63 (50%)

99 (38%)

0.04

  1. ARDS acute respiratory distress syndrome