Skip to main content

Table 2 Baseline characteristics of AHRF patients

From: Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study

 

All patients

ARDS present

ARDS absent

p

N = 385

N = 127

N = 258

Baseline features

 Age (years)—median (IQR)

63 (55–73)

62 (51–71)

64 (56–73)

0.10

 Female—no. (%)

164 (43%)

55 (43%)

109 (42%)

0.84

 SOFA*—median (IQR)

12 (10–14)

14 (11–17)

12 (10–15)

0.002

  Respiration

3 (3–3)

3 (3–4)

3 (3–4)

0.04

  Cardiovascular

4 (1–4)

4 (3–4)

4 (1–4)

0.03

  Central nervous system

4 (3–4)

4 (3–4)

4 (3–4)

0.56

  Liver

0 (0–3)

0 (0–3)

0 (0–3)

0.048

  Coagulation

0 (0–3)

0 (0–3)

0 (0–3)

0.048

  Renal

2 (1–4)

2 (0.5–4)

2 (1–4)

0.38

ARDS/AHRF risk factorno. (%)

 Number of ARDS/AHRF risk factors per patient—median (IQR)

2 (1–3)

3 (2–3)

2 (1–3)

< 0.001

 Shock (non-cardiogenic)

227 (59%)

99 (78%)

128 (50%)

< 0.001

 Transfusion

158 (41%)

58 (46%)

100 (39%)

0.20

 Sepsis (non-pulmonary)

151 (39%)

55 (43%)

96 (37%)

0.30

 Pneumonia

143 (37%)

66 (52%)

77 (30%)

< 0.001

 Aspiration

58 (15%)

28 (22%)

30 (12%)

0.01

 Other

182 (47%)

65 (51%)

117 (45%)

0.33

 None

43 (11%)

3 (2%)

40 (16%)

< 0.001

Intensive care unit settingno. (%)

 Medical

225 (59%)

92 (72%)

133 (52%)

< 0.001

 Cardiac

47 (12%)

4 (3%)

43 (17%)

< 0.001

 Surgical

69 (18%)

23 (18%)

46 (18%)

0.95

 Trauma/burn

39 (10%)

7 (6%)

32 (12%)

0.04

 Neurologic

5 (1%)

1 (1%)

4 (2%)

0.53

  1. AHRF acute hypoxemic respiratory failure, ARDS acute respiratory distress syndrome
  2. *SOFA sequential organ failure assessment. Represents the highest SOFA score within the first 24 h of AHRF onset
  3. Other risk factors for ARDS/AHRF, each present in < 10% of the cohort, include major trauma (9%), major surgery (7%), pulmonary contusion (3%), pancreatitis (2%), major burn (1%), inhalation injury (1%), vasculitis (< 1%), or drowning (0%)