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Table 4 Comparisons of Unyvero vs conventional microbiological methods for all episodes, according to Unyvero version and to previous antibiotic use

From: Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study

Finding

N positive

N negative

Sensitivity

Specificity (%)

PPV (%)

NPV (%)

True

False

True

False

Total (n = 93)

 Pathogen identification

65

6

1

19

77.4

14.3

91.5

5

 Resistance mechanism

19

9

43

22

46.3

82.7

67.9

66.2

P55 cartridge (n = 51)

 Pathogen identification

39

1

1

10

79.6

50

97.5

9

 Resistance mechanism

12

7

21

11

52.1

75

63.2

65.6

HPN cartridge (n = 42)

 Pathogen identification

26

5

0

9

74.3

0

83.9

0

 Resistance mechanism

7

2

22

11

38.9

91.7

77.8

66.7

Previous antimicrobial treatment (n = 75)

 Pathogen identification

54

6

1

14

79.4

14.2

90

6.7

 Resistance mechanism

15

8

31

21

41.7

79.5

65.2

59.6

No previous antimicrobial treatment (n = 18)

 Pathogen identification

13

0

0

5

72.2

0

100

0

 Resistance mechanism

4

1

12

1

80

92.3

80

92.3

  1. Conventional microbiological methods were considered as the gold standard
  2. PPV positive predictive value, NPV negative predictive value, HPN hospitalised pneumonia