Table 1 Demographic data and clinical features
From: Brain tight junction protein expression in sepsis in an autopsy series
Parameter | All, N = 47 | BBB damage, N = 18 | No BBB damage, N = 29 | p |
|---|---|---|---|---|
Age, years, median (percentiles) | 62.5 (56–69) | 61 (56–69) | 63 (60–69.50) | 0.7 |
Sex (male/female) | 34/13 | 14/4 | 20/9 | 0.73 |
APACHE II, admission, median (percentiles) | 24 (18–30) | 27 (22–31) | 24 (17–29) | 0.16 |
SOFA score, admission, median (percentiles) | 11 (7–14) | 11 (8–15) | 11 (7–14) | 0.47 |
SOFA score, maximum, median (percentiles) | 15 (12–17) | 16.5 (15–20) | 14 (11–15.5) | 0.04 |
GCS admission, median (percentiles) | 15 (6–15) | 15 (8–15) | 14 (6–15) | 0.8 |
GCS less than 13, n (%) | 22 (47%) | 9 (50%) | 12 (42%) | 0.48 |
Operated, n (%) | 10 (21.3%) | 2 (11.1%) | 8 (27.6%) | 0.27 |
Intra-abdominal surgery, n (%) | 7 (14.9%) | 2 (11.1%) | 5 (17.2%) | 0.7 |
LOS (days), median (percentiles) | 1.2 (0.6–6.9) | 2.3 (0.96–9.14) | 0.79 (0.4–6.72) | 0.228 |
Septic shock, n (%) | 35 (74.5%) | 14 (78%) | 21 (75%) | 0.74 |
Multiple organ failure, n (%) | 16 (34%) | 6 (12.7%) | 10 (55.6%) | 0.9 |
Received MV, n (%) | 41 (88%) | 17 (95%) | 24 (83%) | 0.384 |
Received ARRT, n (%) | 25 (53%) | 13 (72%) | 12 (42%) | 0.07 |