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Table 4 Predictors of 60-day mortality in 239 critically ill patients with COVID-19 identified using Cox proportional-hazards model

From: Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China

Characteristics Non-survivors (n = 147) Survivors (n = 92) p value Cox proportional-hazards model
Hazard ratio (95% confidence interval) p value
Age ≥ 65 82 (55.8%) 30 (32.6%) < 0.001 1.57 (1.12–2.19) 0.009
Malignancy 11 (7.5%) 2 (2.2%) 0.066 1.62 (0.84–3.14) 0.149
Lymphocyte count < 0.55 × 109/L 73 (50.0%) 30 (32.6%) 0.007 1.23 (0.88–1.73) 0.226
Platelet count < 125 × 109 /L 48 (32.7%) 11 (12.0%) < 0.001 2.01 (1.39–2.91) < 0.001
ARDS 118 (80.3%) 46 (50.0%) < 0.001 1.67 (1.05–2.64) 0.029
Acute cardiac injury 81 (55.1%) 22 (23.9%) < 0.001 0.88 (0.57–1.34) 0.542
AKI 99 (67.4%) 20 (21.7%) < 0.001 2.06 (1.36–3.10) 0.001
Liver dysfunction 127 (86.4%) 64 (69.6%) < 0.001 1.40 (0.77–2.55) 0.264
Coagulopathy 111 (75.5%) 39 (42.4%) < 0.001 1.40 (0.88–2.21) 0.156
  1. ARDS acute respiratory distress syndrome, AKI acute kidney injury
  2. Data were expressed as count (%) unless otherwise
  3. The low limit of normal range of lymphocyte count was 1.1 × 109/L.
  4. The low limit of normal range of platelet count was 125 × 109/L