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Table 4 Predictors of 60-day mortality in 239 critically ill patients with COVID-19 identified using Cox proportional-hazards model

From: Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China

Characteristics

Non-survivors (n = 147)

Survivors (n = 92)

p value

Cox proportional-hazards model

Hazard ratio (95% confidence interval)

p value

Age ≥ 65

82 (55.8%)

30 (32.6%)

< 0.001

1.57 (1.12–2.19)

0.009

Malignancy

11 (7.5%)

2 (2.2%)

0.066

1.62 (0.84–3.14)

0.149

Lymphocyte count < 0.55 × 109/L

73 (50.0%)

30 (32.6%)

0.007

1.23 (0.88–1.73)

0.226

Platelet count < 125 × 109 /L

48 (32.7%)

11 (12.0%)

< 0.001

2.01 (1.39–2.91)

< 0.001

ARDS

118 (80.3%)

46 (50.0%)

< 0.001

1.67 (1.05–2.64)

0.029

Acute cardiac injury

81 (55.1%)

22 (23.9%)

< 0.001

0.88 (0.57–1.34)

0.542

AKI

99 (67.4%)

20 (21.7%)

< 0.001

2.06 (1.36–3.10)

0.001

Liver dysfunction

127 (86.4%)

64 (69.6%)

< 0.001

1.40 (0.77–2.55)

0.264

Coagulopathy

111 (75.5%)

39 (42.4%)

< 0.001

1.40 (0.88–2.21)

0.156

  1. ARDS acute respiratory distress syndrome, AKI acute kidney injury
  2. Data were expressed as count (%) unless otherwise
  3. The low limit of normal range of lymphocyte count was 1.1 × 109/L.
  4. The low limit of normal range of platelet count was 125 × 109/L