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Table 2 Laboratory tests at ICU admission in 239 critically ill patients with COVID-19

From: Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China

Laboratory tests at ICU admission

All patients (n = 239)

Non-survivors (n = 147)

Survivors (n = 92)

p value, survivors vs non-survivors

Hemoglobin, g/L

124.9 ± 17.9

124.8 ± 17.3

124.9 ± 19.0

0.966

White blood cell count, × 109/L

7.9 [5.2–10.7]

8.2 [5.1–11.0]

7.2 [5.2–10.4]

0.444

Neutrophil count, × 109/L

6.9 [4.0–19.7]

7.2 [4.0–9.7]

6.5 [4.0–9.3]

0.485

Lymphocytes, × 109/L

0.6 [0. 5–0.8]

0.6 [0.4–0.8]

0.7 [0.50–0.9]

0.008

Lymphocyte count < 1.1 × 109/L†

219 (91.6%)

139 (94.6%)

80 (87.0%)

0.036

Lymphocyte count < 0.55 × 109/L

103 (43.1%)

73 (50.0%)

30 (32.6%)

0.007

Platelets, × 109 /L

175 [125–219]

160 [110–206]

186 [148–232]

< 0.001

Platelet count < 125 × 109 /L‡

59 (24.7%)

48 (32.7%)

11 (12.0%)

< 0.001

PT, s

11.9 ± 1.7

12.0 ± 1.8

11.6 ± 1.4

0.079

APTT, s

29.3 ± 9.0

29.3 ± 8.9

29.4 ± 10.9

0.988

Total bilirubin, μmol/L

12.5 [10.3–16.8]

13.0 [10.8–18.7]

11.7 [9.5–15.8]

0.029

ALT, U/L

36 [22–56]

35 [21–54]

39 [26–59]

0.210

AST, U/L

41 [33–62]

45 [35–64]

38 [31–61]

0.051

Serum creatinine, U/L

72.1 [58–85.3]

73.2 [59.7–92.5]

70.2 [54.1–81.8]

0.018

hsTNI, pg/mL

85.5 [35.5–133.5]

91.0 [44.0–134.0]

80.0 [30.0–32.0]

0.410

Myoglobin, ng/mL

105.0 [54.0–155.0]

100.0 [54.0–150.0]

110.5 [56.0–162.5]

0.454

IL-6, pg/mL‖

9.1 [6.7–12.0]

9.1 [7.1–12.9]

9.1 [6.2–11.7]

0.385

Elevated IL-6 level

185 (77.4%)

119 (81.0%)

66 (71.7%)

0.068

Arterial blood gas analysis*

 pH

7.46 ± 0.07

7.46 ± 0.08

7.45 ± 0.05

0.496

 pO2/FiO2, mm Hg

91.3 [66.6–133.5]

82.4 [61.6–120.4]

109.0 [77.5–155.6]

0.005

 pCO2, mmHg

35.1 ± 10.8

35.6 ± 12.9

34.4 ± 6.0

0.477

 HCO3−, mmol/L

24.4 ± 4.0

24.3 ± 4.4

24.5 ± 3.3

0.839

  1. COVID-19 coronavirus disease 2019, ICU intensive care unit, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase, hsTNI hypersensitive troponin I, IL-6 interleukin 6, pO2 partial pressure of oxygen, FiO2 fraction of inspired oxygen, pCO2 partial pressure of carbon dioxide
  2. Data were expressed median [interquartile range] or as mean ± standard deviation
  3. †The lower limit of normal range of lymphocyte count was 1.1 × 109/L
  4. ‡The lower limit of normal range of platelet count was 125 × 109/L
  5. ‖IL-6 analysis was conducted in 114 non-survivors and 67 survivors
  6. The upper limit of normal range was 7 pg/ml
  7. *Arterial blood gas analysis was conducted in 101 non-survivors and 64 survivors
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Critical Care

ISSN: 1364-8535