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Table 2 Laboratory tests at ICU admission in 239 critically ill patients with COVID-19

From: Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China

Laboratory tests at ICU admission All patients (n = 239) Non-survivors (n = 147) Survivors (n = 92) p value, survivors vs non-survivors
Hemoglobin, g/L 124.9 ± 17.9 124.8 ± 17.3 124.9 ± 19.0 0.966
White blood cell count, × 109/L 7.9 [5.2–10.7] 8.2 [5.1–11.0] 7.2 [5.2–10.4] 0.444
Neutrophil count, × 109/L 6.9 [4.0–19.7] 7.2 [4.0–9.7] 6.5 [4.0–9.3] 0.485
Lymphocytes, × 109/L 0.6 [0. 5–0.8] 0.6 [0.4–0.8] 0.7 [0.50–0.9] 0.008
Lymphocyte count < 1.1 × 109/L 219 (91.6%) 139 (94.6%) 80 (87.0%) 0.036
Lymphocyte count < 0.55 × 109/L 103 (43.1%) 73 (50.0%) 30 (32.6%) 0.007
Platelets, × 109 /L 175 [125–219] 160 [110–206] 186 [148–232] < 0.001
Platelet count < 125 × 109 /L 59 (24.7%) 48 (32.7%) 11 (12.0%) < 0.001
PT, s 11.9 ± 1.7 12.0 ± 1.8 11.6 ± 1.4 0.079
APTT, s 29.3 ± 9.0 29.3 ± 8.9 29.4 ± 10.9 0.988
Total bilirubin, μmol/L 12.5 [10.3–16.8] 13.0 [10.8–18.7] 11.7 [9.5–15.8] 0.029
ALT, U/L 36 [22–56] 35 [21–54] 39 [26–59] 0.210
AST, U/L 41 [33–62] 45 [35–64] 38 [31–61] 0.051
Serum creatinine, U/L 72.1 [58–85.3] 73.2 [59.7–92.5] 70.2 [54.1–81.8] 0.018
hsTNI, pg/mL 85.5 [35.5–133.5] 91.0 [44.0–134.0] 80.0 [30.0–32.0] 0.410
Myoglobin, ng/mL 105.0 [54.0–155.0] 100.0 [54.0–150.0] 110.5 [56.0–162.5] 0.454
IL-6, pg/mL 9.1 [6.7–12.0] 9.1 [7.1–12.9] 9.1 [6.2–11.7] 0.385
Elevated IL-6 level 185 (77.4%) 119 (81.0%) 66 (71.7%) 0.068
Arterial blood gas analysis*
 pH 7.46 ± 0.07 7.46 ± 0.08 7.45 ± 0.05 0.496
 pO2/FiO2, mm Hg 91.3 [66.6–133.5] 82.4 [61.6–120.4] 109.0 [77.5–155.6] 0.005
 pCO2, mmHg 35.1 ± 10.8 35.6 ± 12.9 34.4 ± 6.0 0.477
 HCO3, mmol/L 24.4 ± 4.0 24.3 ± 4.4 24.5 ± 3.3 0.839
  1. COVID-19 coronavirus disease 2019, ICU intensive care unit, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase, hsTNI hypersensitive troponin I, IL-6 interleukin 6, pO2 partial pressure of oxygen, FiO2 fraction of inspired oxygen, pCO2 partial pressure of carbon dioxide
  2. Data were expressed median [interquartile range] or as mean ± standard deviation
  3. The lower limit of normal range of lymphocyte count was 1.1 × 109/L
  4. The lower limit of normal range of platelet count was 125 × 109/L
  5. IL-6 analysis was conducted in 114 non-survivors and 67 survivors
  6. The upper limit of normal range was 7 pg/ml
  7. *Arterial blood gas analysis was conducted in 101 non-survivors and 64 survivors