TY - JOUR AU - Iba, Toshiaki AU - Levy, Jerrold H. AU - Connors, Jean Marie AU - Warkentin, Theodore E. AU - Thachil, Jecko AU - Levi, Marcel PY - 2020 DA - 2020/06/18 TI - The unique characteristics of COVID-19 coagulopathy JO - Critical Care SP - 360 VL - 24 IS - 1 AB - Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen with bacterial sepsis-induced coagulopathy (SIC) and disseminated intravascular coagulation (DIC), with CAC usually showing increased D-dimer and fibrinogen levels but initially minimal abnormalities in prothrombin time and platelet count. Venous thromboembolism and arterial thrombosis are more frequent in CAC compared to SIC/DIC. Clinical and laboratory features of CAC overlap somewhat with a hemophagocytic syndrome, antiphospholipid syndrome, and thrombotic microangiopathy. We summarize the key characteristics of representative coagulopathies, discussing similarities and differences so as to define the unique character of CAC. SN - 1364-8535 UR - https://doi.org/10.1186/s13054-020-03077-0 DO - 10.1186/s13054-020-03077-0 ID - Iba2020 ER -