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Table 2 Impact of PaO2/FiO2, PaO2 and PaCO2 on hospital mortality

From: The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study

Variable

Incidence, n (%)

Hospital mortality, n (%)

Unadjusted odds ratio for hospital mortality (95% CI)

Adjusted odds ratio for hospital mortality (95% CI)

PaO2/FiO2a

 ≤ 100 mmHg

3314/23,624 (14.0%)

2268/3314 (68.4%)

2.18 (1.98–2.39), P < 0.001

1.79 (1.48–2.15), P < 0.001

 101–200 mmHg

8393/23,624 (35.5%)

5304/8393 (63.2%)

1.72 (1.60–1.85), P < 0.001

1.63 (1.45–1.84), P < 0.001

 201–300 mmHg

7313/23,624 (31.0%)

4105/7313 (56.1%)

1.28 (1.19–1.38), P < 0.001

1.36 (1.21–1.53), P < 0.001

 > 300 mmHg

4604/23,624 (19.5%)

2298/4604 (49.9%)

1 (Reference category)

1 (Reference category)

PaO2b

 Hypoxemia

4135/23,625 (17.5%)

2704/4135 (65.4%)

1.61 (1.45–1.80), P < 0.001

1.34 (1.10–1.65), P = 0.004

 Normoxia

17,480/23,625 (74.0%)

10,187 / 17,480 (58.3%)

1.19 (1.09–1.31), P < 1.001

1.15 (0.98–1.35), P = 0.082

 Hyperoxemia

2010/23,625 (8.5%)

1085/2010 (54.0%)

1 (Reference category)

1 (Reference category)

PaCO2a

 ≤ 35 mmHg

5554/23,625 (23.5%)

3621/5554 (65.2%)

1.44 (1.34–1.54), P < 0.001

1.91 (1.63–2.24), P < 0.001

 36–45 mmHg

9910/23,625 (41.9%)

5605/9910 (56.6%)

1 (Reference category)

1 (Reference category)

 46–50 mmHg

3444/23,625 (14.6%)

1906/3444 (55.3%)

0.95 (0.88–1.03), P = 0.215

0.69 (0.55–0.86), P = 0.001

 51–55 mmHg

1958/23,625 (8.3%)

1079/1958 (55.1%)

0.94 (0.86–1.04), P = 0.237

0.74 (0.53–1.04), P = 0.079

 > 55 mmHg

2759/23,625 (11.7%)

1765/2759 (64.0%)

1.36 (1.25–1.49), P < 0.001

0.40 (0.23–0.70), P = 0.001

  1. aReported using logistic regression model 1, data missing on n = 1
  2. bReported using logistic regression model 2