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Table 1 Demographics and clinical features of coronavirus disease 2019

From: Clinical features and outcomes of COVID-19 patients with gastrointestinal symptoms

 

Total (n = 157)

GI symptoms(n = 63)

Without GI symptoms (n = 94)

p value*

Age, mean (SD), years

49.3 (14.5)

51.9 (14.9)

47.5 (14.0)

0.0599

Gender

 Male

74 (47.1%)

24 (38.1%)

50 (53.2%)

0.0633

 Female

83 (52.9%)

39 (61.9%)

44 (46.8%)

Comorbidities

 Hypertension

28 (17.8%)

12 (19.1%)

16 (17.0%)

0.7451

 Diabetes

9 (5.7%)

5 (7.9%)

4 (4.3%)

0.5337

 Chronic kidney disease

3 (1.9%)

1 (1.6%)

2 (2.1%)

1.0000

 Chronic lung disease

2 (1.3%)

1 (1.6%)

1 (1.1%)

1.0000

 Heart disease

2 (1.3%)

2 (3.2%)

0

0.1595

 Malignancy

4 (2.6%)

1 (1.6%)

3 (3.2%)

0.9135

 Total with ≥ 1 comorbidity

55 (35.0%)

24 (38.1%)

31 (33.0%)

0.5101

Symptoms

 Fever

65 (41.4%)

23 (36.5%)

42 (44.7%)

0.3082

 Cough

109 (69.4%)

47 (74.6%)

62 (66.0%)

0.2491

 Sore throat

12 (7.6%)

4 (6.4%)

8 (8.5%)

0.8468

 Muscle soreness

44 (28.0%)

23 (36.5%)

21 (22.3%)

0.0527

 Fatigue

73 (46.5%)

44 (69.8%)

29 (30.9%)

< 0.001

Initial laboratory parameters, median (IQR)

 WBCs count, × 109/L

4.9 (3.8–6.3)

4.9 (3.4–6.0)

5.0 (4.0–6.4)

0.4838

 Lymphocyte count, × 109/L

1.0 (0.7–1.4)

1.0 (0.7–1.4)

1.0 (0.7–1.5)

0.4423

 C-reactive protein, mg/L

13.2 (3.4–32.9)

17.8 (7.2–41.1)

9.1 (2.9–30.3)

0.0561

 ALT level, IU/L

21.7 (15.4–38.8)

23.1 (15.0–43.0)

21.7 (16.2–34.3)

0.8062

 AST level, IU/L

26.2 (20.7–34.7)

26.0 (20.0–35.0)

26.9 (20.8–34.7)

0.7189

Severe cases

41 (26.1%)

8 (12.7%)

33 (35.1%)

0.0016

Corticosteroid usage

112 (71.3%)

40 (63.5%)

72 (76.6%)

0.0751

Hospital course, mean (SD), days

 Duration onset to treatment

5.3 (5.4)

5.9 (6.0)

4.9 (4.9)

0.2580

 Clinical recovery time

9.8 (4.9)

10.7 (4.5)

9.1 (5.2)

0.0607

 Time of virus nucleic acid turn to negative

12.4 (6.4)

13.0 (6.1)

12.0 (6.7)

0.3509

 Hospitalization duration

16.0 (4.9)

16.1 (5.1)

15.8 (4.7)

0.7003

  1. GI gastrointestinal, IQR interquartile range, SD standard deviation, WBC white blood cell, ALT alanine aminotransferase, AST aspartate aminotransferase
  2. *P values indicate differences between patients with GI symptoms and those without. P < 0.05 was defined as statistically significant