From: Clinical features and outcomes of COVID-19 patients with gastrointestinal symptoms
 | Total (n = 157) | GI symptoms(n = 63) | Without GI symptoms (n = 94) | p value* |
---|---|---|---|---|
Age, mean (SD), years | 49.3 (14.5) | 51.9 (14.9) | 47.5 (14.0) | 0.0599 |
Gender | ||||
 Male | 74 (47.1%) | 24 (38.1%) | 50 (53.2%) | 0.0633 |
 Female | 83 (52.9%) | 39 (61.9%) | 44 (46.8%) | |
Comorbidities | ||||
 Hypertension | 28 (17.8%) | 12 (19.1%) | 16 (17.0%) | 0.7451 |
 Diabetes | 9 (5.7%) | 5 (7.9%) | 4 (4.3%) | 0.5337 |
 Chronic kidney disease | 3 (1.9%) | 1 (1.6%) | 2 (2.1%) | 1.0000 |
 Chronic lung disease | 2 (1.3%) | 1 (1.6%) | 1 (1.1%) | 1.0000 |
 Heart disease | 2 (1.3%) | 2 (3.2%) | 0 | 0.1595 |
 Malignancy | 4 (2.6%) | 1 (1.6%) | 3 (3.2%) | 0.9135 |
 Total with ≥ 1 comorbidity | 55 (35.0%) | 24 (38.1%) | 31 (33.0%) | 0.5101 |
Symptoms | ||||
 Fever | 65 (41.4%) | 23 (36.5%) | 42 (44.7%) | 0.3082 |
 Cough | 109 (69.4%) | 47 (74.6%) | 62 (66.0%) | 0.2491 |
 Sore throat | 12 (7.6%) | 4 (6.4%) | 8 (8.5%) | 0.8468 |
 Muscle soreness | 44 (28.0%) | 23 (36.5%) | 21 (22.3%) | 0.0527 |
 Fatigue | 73 (46.5%) | 44 (69.8%) | 29 (30.9%) | < 0.001 |
Initial laboratory parameters, median (IQR) | ||||
 WBCs count, × 109/L | 4.9 (3.8–6.3) | 4.9 (3.4–6.0) | 5.0 (4.0–6.4) | 0.4838 |
 Lymphocyte count, × 109/L | 1.0 (0.7–1.4) | 1.0 (0.7–1.4) | 1.0 (0.7–1.5) | 0.4423 |
 C-reactive protein, mg/L | 13.2 (3.4–32.9) | 17.8 (7.2–41.1) | 9.1 (2.9–30.3) | 0.0561 |
 ALT level, IU/L | 21.7 (15.4–38.8) | 23.1 (15.0–43.0) | 21.7 (16.2–34.3) | 0.8062 |
 AST level, IU/L | 26.2 (20.7–34.7) | 26.0 (20.0–35.0) | 26.9 (20.8–34.7) | 0.7189 |
Severe cases | 41 (26.1%) | 8 (12.7%) | 33 (35.1%) | 0.0016 |
Corticosteroid usage | 112 (71.3%) | 40 (63.5%) | 72 (76.6%) | 0.0751 |
Hospital course, mean (SD), days | ||||
 Duration onset to treatment | 5.3 (5.4) | 5.9 (6.0) | 4.9 (4.9) | 0.2580 |
 Clinical recovery time | 9.8 (4.9) | 10.7 (4.5) | 9.1 (5.2) | 0.0607 |
 Time of virus nucleic acid turn to negative | 12.4 (6.4) | 13.0 (6.1) | 12.0 (6.7) | 0.3509 |
 Hospitalization duration | 16.0 (4.9) | 16.1 (5.1) | 15.8 (4.7) | 0.7003 |