Variables | PEEP (cmH2O) |
---|
3 | 5.5 | 7.5 | 9.5 | 11 |
---|
VT(ml) | 2.2 ± 0.2 | 2.2 ± 0.0 | 2.1 ± 0.1 | 2.0 ± 0.1 | 2.2 ± 0.3 |
RR (bpm) | 75 ± 8 | 74 ± 2 | 75 ± 5 | 81 ± 4 | 75 ± 9 |
Ppeak (cmH2O) | 12.2 ± 1.8 | 15.1 ± 0.7 | 17.4 ± 1.2* | 22.3 ± 2.4*#& | 30.1 ± 4.3*#&** |
Pplat (cmH2O) | 9.7 ± 1.4 | 12.9 ± 0.6* | 15.1 ± 0.8*# | 18.3 ± 2.5*#& | 24.2 ± 3.1*#&** |
ΔP (cmH2O) | 8.4 ± 1.4 | 8.8 ± 0.6 | 9.5 ± 0.4 | 10.5 ± 2.3 | 14.7 ± 2.9*#&** |
- Values are means + SD of 6 animals/group
- One-way ANOVA followed by the Bonferroni post hoc test was performed
- VT tidal volume, RR respiratory rate, Ppeak respiratory system peak pressure, Pplat respiratory system end-inspiratory (plateau) pressure, ΔP driving pressure, PEEP positive end-expiratory pressure
- *Significantly different from PEEP 3 (p < 0.05)
- #Significantly different from PEEP 5.5 (p < 0.05)
- &Significantly different from PEEP 7.5 (p < 0.05)
- **Significantly different from PEEP 9.5 (p < 0.05)