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Table 5 Outcomes with univariate testing comparing non-iGAS patients with iGAS patients. Values are median (Q1–Q3) or number (%)

From: Morbidity and mortality in critically ill patients with invasive group A streptococcus infection: an observational study

 

Non-iGAS, n = 968

iGAS, n = 53

p valuea

DAFb vasopressor

24 (25–26)

25 (22–26)

0.04*

Vasopressor free daysc

24 (0–26)

25 (23–26)

0.027*

DAFb ventilator

23 (3–28)

25 (20–28)

0.02*

Ventilator free daysc

23 (0–28)

25 (19–28)

0.046*

CRRTd

185 (19)

12 (23)

0.48

AKIN-creae

0 (0–3)

3 (0–3)

0.045*

SOFA maxf

11 (8–14)

10 (6–14)

0.16

Length of stay, survivors

3.3 (1.5–6.8)

3.8 (1.8–7.0)

0.77

ICU mortality

237 (25)

3 (5.7)

< 0.001*

28-day mortality

354 (37)

7 (13)

< 0.001*

90-day mortality

429 (44)

9 (17)

< 0.001*

180-day mortality

471 (49)

12 (23)

< 0.001*

  1. aMann-Whitney or Fisher’s exact test (two-tailed)
  2. bDays alive and free without extra penalty for death
  3. cWith extra penalty for death
  4. dContinuous renal replacement therapy
  5. eMaximal Acute Kidney Injury Network classification score the first 10 days after admission
  6. fMaximal Sequential Organ Failure Assessment, score during ICU admission