Table 1 Baseline characteristics and clinical outcomes stratified by median NLR value

Baseline characteristics

Non-ARDS N = 37

ARDS N = 44

P values

 Age

49 (36.5–62.5)

53.5(43–70.5)

0.110

 Gender/case (%)

0.891

  Male

23 (62.3%)

28 (63.6%)

  Female

14 (37.8%)

16 (36.4%)

 BMI (kg/m²)

23.05 (22.00–27.25)

24.78(21.29–27.41)

0.816

 Smoking/case (%)

1 (2.7%)

2 (4.5%)

1.000

  Diabetes

3 (8.1%)

15 (34.15)

0.007

  Hypertension

7 (18.9%)

8 (18.2%)

0.932

  Chronic pulmonary disease

2 (5.4%)

9 (20.5%)

0.049

  Cardiovascular disease

2 (5.4%)

2 (4.5%)

1.000

  Cerebrovascular disease

0 (0%)

3 (6.8%)

0.246

  Renal disease

1 (2.7%)

2 (4.5%)

1.000

  Liver disease

2 (5.4%)

2 (4.5%)

1.000

  MAP/mmHg

94.67 (89.17–100.50)

97.83(91.75,108.84)

0.162

  Heart rate (beats/min)

88 (77.5–99)

92.5 (85.25–104)

0.175

  Respiratory rate (breaths/min)

20 (20–22.5)

21 (20–23)

0.107

  Pulse oxygen saturation/%

96 (93.75–97.25)

95 (90.25–97)

0.486

  WBC/10⁹/L

5.43 (4.05–6.59)

6.47 (3.94–9.62)

0.122

  Hemoglobin/g/L

141 (127–153.5)

132 (117.25–146.5)

0.107

  Total bilirubin (μmol/L)

9 (5.93–15.6)

9.3 (6.65–14.3)

0.927

  AST (IU/L)

30.5 (19–39.75)

29.15 (15.75–57.68)

0.764

  ALT (IU/L)

30 (25–39.8)

35 (25.75–51.6)

0.221

  Creatinine (μmol/L)

71.75 (54.35–79.75)

69.2 (54.63–80.53)

0.980

  PT/s

12.7 (12.5–13.98)

13.1 (12.6–13.8)

0.787

  APTT/s

32.75 (29.1–40.13)

31.3 (28.8–35.5)

0.246

  NLR/%

6.4 (3.75–13.1)

13.55 (6.05–24.13)

0.002

Clinical outcomes

Low NLR N = 41

High NLR N = 40

P value

  High-flow nasal cannula

15 (36.6%)

16 (40%)

0.752

  Noninvasive ventilation

5 (12.2%)

17 (42.5%)

0.002

  Invasive ventilation

2 (4.9%)

8 (20%)

0.048

  Mild-moderate ARDS

11 (26.8%)

11 (27.5%)

0.946

  Moderate-severe ARDS

5 (12.2%)

11 (42.5%)

0.002